Low-grade inflammation as a predictor of antidepressant and anti-inflammatory therapy response in MDD patients: a systematic review of the literature in combination …
G Arteaga-Henríquez, MS Simon, B Burger… - Frontiers in …, 2019 - frontiersin.org
Low-grade inflammation plays a role not only in the pathogenesis of major depressive
disorder (MDD) but probably also in the poor responsiveness to regular antidepressants …
disorder (MDD) but probably also in the poor responsiveness to regular antidepressants …
Therapeutic implications of brain–immune interactions: treatment in translation
A wealth of data has been amassed that details a complex, yet accessible, series of
pathways by which the immune system, notably inflammation, can influence the brain and …
pathways by which the immune system, notably inflammation, can influence the brain and …
Multifaceted effects of oligodendroglial exosomes on neurons: impact on neuronal firing rate, signal transduction and gene regulation
D Fröhlich, WP Kuo, C Frühbeis… - … of the Royal …, 2014 - royalsocietypublishing.org
Exosomes are small membranous vesicles of endocytic origin that are released by almost
every cell type. They exert versatile functions in intercellular communication important for …
every cell type. They exert versatile functions in intercellular communication important for …
Mechanisms of microglia-mediated neurotoxicity in a new model of the stroke penumbra
V Kaushal, LC Schlichter - Journal of Neuroscience, 2008 - Soc Neuroscience
After an ischemic stroke, neurons in the core are rapidly committed to die, whereas neuron
death in the slowly developing penumbra is more amenable to therapeutic intervention …
death in the slowly developing penumbra is more amenable to therapeutic intervention …
Role of nitric oxide after brain ischaemia
Ischaemic stroke is the second or third leading cause of death in developed countries. In the
last two decades substantial research and efforts have been made to understand the …
last two decades substantial research and efforts have been made to understand the …
Neuroprotection afforded by prior citicoline administration in experimental brain ischemia: effects on glutamate transport
BACKGROUND AND PURPOSE:: Cytidine-5′-diphosphocholine (citicoline or CDP-
choline), an intermediate in the biosynthesis of phosphatidylcholine, has shown beneficial …
choline), an intermediate in the biosynthesis of phosphatidylcholine, has shown beneficial …
Mitochondrial respiratory chain and free radical generation in stroke
Being the second most common cause of death in the industrial countries and one of the
major causes of death and disability, stroke has a great effect on public health and is the …
major causes of death and disability, stroke has a great effect on public health and is the …
Neuroprotective effect of 20 (S)-ginsenoside Rg3 on cerebral ischemia in rats
J Tian, F Fu, M Geng, Y Jiang, J Yang, W Jiang… - Neuroscience …, 2005 - Elsevier
This study was conducted to investigate the neuroprotective effects of 20 (S)-ginsenoside
Rg3 on focal cerebral ischemia in rats. Middle cerebral artery occlusion (MCAO) model in …
Rg3 on focal cerebral ischemia in rats. Middle cerebral artery occlusion (MCAO) model in …
Mitochondria and reactive oxygen and nitrogen species in neurological disorders and stroke: therapeutic implications
Mitochondria represent both the main source and target of reactive oxygen and nitrogen
species (RONS). In view of the large energy expenditure made by neurons during …
species (RONS). In view of the large energy expenditure made by neurons during …
Phosphorylation of tau at Y18, but not tau-fyn binding, is required for tau to modulate NMDA receptor-dependent excitotoxicity in primary neuronal culture
T Miyamoto, L Stein, R Thomas, B Djukic… - Molecular …, 2017 - Springer
Background Hyperexcitability of neuronal networks can lead to excessive release of the
excitatory neurotransmitter glutamate, which in turn can cause neuronal damage by …
excitatory neurotransmitter glutamate, which in turn can cause neuronal damage by …