Breast cancer is the most common cancer among women and is considered a developed
country disease. Moreover, is a heterogenous disease, existing different types and stages of …

Type 2 diabetes mellitus (T2DM) is associated with a higher risk of cancer and cancer-
related mortality. Increased blood glucose and insulin levels in T2DM patients may be, at …

Breast cancer is one of the most common cancers worldwide with a rising incidence, and is
the leading cause of cancer-related death among females. Angiogenesis plays an important …

Abstract Combretastatin A-4 (CA4) is the lead compound of a relatively new class of
vascular disrupting agents that target existing tumor blood vessels. Recent studies showed …

Glipizide (GLZ) is an oral hypoglycemic agent, which is a weakly aqueous soluble drug. The
solubility values of GLZ in various neat solvents are scarce in the literature. Hence, the …

Studies have indicated that platelets play an important role in tumorigenesis, and an
abundance of platelets accumulate in the ovarian tumor microenvironment outside the …

Melanoma cell metastasis is the main cause of patient death. To develop more effective
strategies for the prevention or treatment of melanoma, we investigated the inhibitory effects …

Beta-Caryophyllene (BCP), a naturally occurring sesquiterpene abundantly found in cloves,
hops, and cannabis, is the active candidate of a relatively new group of vascular-inhibiting …

Abstract In 2010, the European Parliament and the European Union adopted a directive on
the protection of animals used for scientific purposes. The directive aims to protect animals …

Angiogenesis, the process of new blood vessel formation from pre‐existing vessels, is
essential for growth and development. Development of drugs that can accelerate or …