Role and mechanisms of cytokines in the secondary brain injury after intracerebral hemorrhage
H Zhu, Z Wang, J Yu, X Yang, F He, Z Liu, F Che… - Progress in …, 2019 - Elsevier
Intracerebral hemorrhage (ICH) is a common and severe cerebrovascular disease that has
high mortality. Few survivors achieve self-care. Currently, patients receive only symptomatic …
high mortality. Few survivors achieve self-care. Currently, patients receive only symptomatic …
From stroke to dementia: a comprehensive review exposing tight interactions between stroke and amyloid-β formation
R Goulay, L Mena Romo, EM Hol… - Translational Stroke …, 2020 - Springer
Stroke and Alzheimer's disease (AD) are cerebral pathologies with high socioeconomic
impact that can occur together and mutually interact. Vascular factors predisposing to …
impact that can occur together and mutually interact. Vascular factors predisposing to …
Understanding the pathophysiology of cerebral amyloid angiopathy
Cerebral amyloid angiopathy (CAA), one of the main types of cerebral small vessel disease,
is a major cause of spontaneous intracerebral haemorrhage and an important contributor to …
is a major cause of spontaneous intracerebral haemorrhage and an important contributor to …
GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia
Genome-wide association studies (GWAS) have identified> 80 Alzheimer's disease and
related dementias (ADRD)-associated genetic loci. However, the clinical outcomes used in …
related dementias (ADRD)-associated genetic loci. However, the clinical outcomes used in …
CNS border-associated macrophages: ontogeny and potential implication in disease
I Dermitzakis, P Theotokis, P Evangelidis… - Current Issues in …, 2023 - mdpi.com
Being immune privileged, the central nervous system (CNS) is constituted by unique
parenchymal and non-parenchymal tissue-resident macrophages, namely, microglia and …
parenchymal and non-parenchymal tissue-resident macrophages, namely, microglia and …
Differences in the cerebral amyloid angiopathy proteome in Alzheimer's disease and mild cognitive impairment
D Leitner, T Kavanagh, E Kanshin, K Balcomb… - Acta …, 2024 - Springer
Cerebral amyloid angiopathy (CAA) is characterized by amyloid beta (Aβ) deposition in
cerebrovasculature. It is prevalent with aging and Alzheimer's disease (AD), associated with …
cerebrovasculature. It is prevalent with aging and Alzheimer's disease (AD), associated with …
Innate immunity stimulation via CpG oligodeoxynucleotides ameliorates Alzheimer's disease pathology in aged squirrel monkeys
AG Patel, PN Nehete, SR Krivoshik, X Pei, EL Cho… - Brain, 2021 - academic.oup.com
Alzheimer's disease is the most common cause of dementia and the only illness among the
top 10 causes of death for which there is no disease-modifying therapy. The failure rate of …
top 10 causes of death for which there is no disease-modifying therapy. The failure rate of …
“Amyloid‐beta accumulation cycle” as a prevention and/or therapy target for Alzheimer's disease
The cell cycle and its regulators are validated targets for cancer drugs. Reagents that target
cells in a specific cell cycle phase (eg, antimitotics or DNA synthesis inhibitors/replication …
cells in a specific cell cycle phase (eg, antimitotics or DNA synthesis inhibitors/replication …
Impact of cerebral amyloid angiopathy in two transgenic mouse models of cerebral β-amyloidosis: a neuropathological study
P Marazuela, B Paez-Montserrat… - International journal of …, 2022 - mdpi.com
The pathological accumulation of parenchymal and vascular amyloid-beta (Aβ) are the main
hallmarks of Alzheimer's disease (AD) and Cerebral Amyloid Angiopathy (CAA) …
hallmarks of Alzheimer's disease (AD) and Cerebral Amyloid Angiopathy (CAA) …
Development and validation of a nomogram to predict the 30-day mortality risk of patients with intracerebral hemorrhage
J Zou, H Chen, C Liu, Z Cai, J Yang, Y Zhang… - Frontiers in …, 2022 - frontiersin.org
Background Intracerebral hemorrhage (ICH) is a stroke syndrome with an unfavorable
prognosis. Currently, there is no comprehensive clinical indicator for mortality prediction of …
prognosis. Currently, there is no comprehensive clinical indicator for mortality prediction of …