Inflammation and colon cancer
The connection between inflammation and tumorigenesis is well-established and in the last
decade has received a great deal of supporting evidence from genetic, pharmacological …
decade has received a great deal of supporting evidence from genetic, pharmacological …
CD147 receptor is essential for TFF3-mediated signaling regulating colorectal cancer progression
HY Cui, SJ Wang, F Song, X Cheng, G Nan… - … and Targeted Therapy, 2021 - nature.com
Major gaps in understanding the molecular mechanisms of colorectal cancer (CRC)
progression and intestinal mucosal repair have hampered therapeutic development for …
progression and intestinal mucosal repair have hampered therapeutic development for …
Trefoil factor family peptides–friends or foes?
M Busch, N Dünker - Biomolecular concepts, 2015 - degruyter.com
Trefoil factor family (TFF) peptides are a group of molecules bearing a characteristic three-
loop trefoil domain. They are mainly secreted in mucous epithelia together with mucins but …
loop trefoil domain. They are mainly secreted in mucous epithelia together with mucins but …
Müller glia as an important source of cytokines and inflammatory factors present in the gliotic retina during proliferative vitreoretinopathy
K Eastlake, PJ Banerjee, A Angbohang, DG Charteris… - Glia, 2016 - Wiley Online Library
Retinal gliosis is characterized by biochemical and physiological changes that often lead to
Müller glia proliferation and hypertrophy and is a feature of many neuro‐degenerative and …
Müller glia proliferation and hypertrophy and is a feature of many neuro‐degenerative and …
Dietary kaempferol suppresses inflammation of dextran sulfate sodium-induced colitis in mice
MY Park, GE Ji, MK Sung - Digestive diseases and sciences, 2012 - Springer
Background In ulcerative colitis (UC), reduction of inflammation may represent a key
mechanism in UC therapy, and anti-inflammatory agents would be good candidates for …
mechanism in UC therapy, and anti-inflammatory agents would be good candidates for …
[HTML][HTML] TFF3 is a normal breast epithelial protein and is associated with differentiated phenotype in early breast cancer but predisposes to invasion and metastasis in …
ARH Ahmed, AB Griffiths, MT Tilby, BR Westley… - The American journal of …, 2012 - Elsevier
The trefoil protein TFF3 stimulates invasion and angiogenesis in vitro. To determine whether
it has a role in breast tumor metastasis and angiogenesis, its levels were measured by …
it has a role in breast tumor metastasis and angiogenesis, its levels were measured by …
Trefoil factor 3 is oncogenic and mediates anti-estrogen resistance in human mammary carcinoma
We report herein that trefoil factor 3 (TFF3) is oncogenic and mediates anti-estrogen
resistance in human mammary carcinoma. Forced expression of TFF3 in mammary …
resistance in human mammary carcinoma. Forced expression of TFF3 in mammary …
Trefoil factor 1 stimulates both pancreatic cancer and stellate cells and increases metastasis
T Arumugam, W Brandt, V Ramachandran, TT Moore… - Pancreas, 2011 - journals.lww.com
Objectives: Trefoil factor 1 (TFF1) is a stable secretory protein expressed widely in the
gastrointestinal mucosa that is also expressed in pancreatic ductal adenocarcinoma …
gastrointestinal mucosa that is also expressed in pancreatic ductal adenocarcinoma …
[HTML][HTML] TFF3 contributes to epithelial-mesenchymal transition (EMT) in papillary thyroid carcinoma cells via the MAPK/ERK signaling pathway
X Lin, H Zhang, J Dai, W Zhang, J Zhang, G Xue… - Journal of …, 2018 - ncbi.nlm.nih.gov
Trefoil factor 3 (TFF3) was found to be overexpressed in many types of tumours. Evidence
has shown that TFF3 plays an important role in tumour proliferation, migration and invasion …
has shown that TFF3 plays an important role in tumour proliferation, migration and invasion …
[HTML][HTML] Reduced expression of TFF1 and increased expression of TFF3 in gastric cancer: correlation with clinicopathological parameters and prognosis
S Im, C Yoo, JH Jung, HJ Choi, J Yoo… - International journal of …, 2013 - ncbi.nlm.nih.gov
Objectives: The trefoil factor family (TFF) is composed of three thermostable, and protease-
resistant proteins, named TFF1, TFF2 and TFF3, and plays a role in gastrointestinal mucosal …
resistant proteins, named TFF1, TFF2 and TFF3, and plays a role in gastrointestinal mucosal …