Toxins-antitoxins: diversity, evolution and function

F Hayes, L Van Melderen - Critical reviews in biochemistry and …, 2011 - Taylor & Francis
Genes for toxin-antitoxin (TA) complexes are widespread in prokaryote genomes, and
species frequently possess tens of plasmid and chromosomal TA loci. The complexes are …

Addiction modules and programmed cell death and antideath in bacterial cultures

H Engelberg-Kulka, G Glaser - Annual Reviews in Microbiology, 1999 - annualreviews.org
▪ Abstract In bacteria, programmed cell death is mediated through “addiction modules”
consisting of two genes. The product of the second gene is a stable toxin, whereas the …

Common virulence factors for bacterial pathogenicity in plants and animals

LG Rahme, EJ Stevens, SF Wolfort, J Shao… - Science, 1995 - science.org
A Pseudomonas aeruginosa strain (UCBPP-PA14) is infectious both in an Arabidopsis
thaliana leaf infiltration model and in a mouse full-thickness skin burn model. UCBPP-PA14 …

Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis

MW Tan, S Mahajan-Miklos… - Proceedings of the …, 1999 - National Acad Sciences
We show that a single clinical isolate of the human opportunistic pathogen Pseudomonas
aeruginosa (strain PA14), which previously was shown to be pathogenic in mice and plants …

Control of Acid Resistance inEscherichia coli

MP Castanie-Cornet, TA Penfound, D Smith… - Journal of …, 1999 - Am Soc Microbiol
Acid resistance (AR) in Escherichia coli is defined as the ability to withstand an acid
challenge of pH 2.5 or less and is a trait generally restricted to stationary-phase cells. Earlier …

A set of recombineering plasmids for gram-negative bacteria

S Datta, N Costantino, DL Court - Gene, 2006 - Elsevier
We have constructed a set of plasmids that can be used to express recombineering
functions in some gram-negative bacteria, thereby facilitating in vivo genetic manipulations …

Complete nucleotide sequence of Birmingham IncPα plasmids: compilation and comparative analysis

W Pansegrau, E Lanka, PT Barth, DH Figurski… - Journal of molecular …, 1994 - Elsevier
The IncPα promiscuous plasmid (R18, R68, RK2, RP1 and RP4) comprises 60,099 bp of
nucleotide sequence, encoding at least 74 genes. About 40 kb of the genome, designated …

Use of model plant hosts to identify Pseudomonas aeruginosa virulence factors

LG Rahme, MW Tan, L Le, SM Wong… - Proceedings of the …, 1997 - National Acad Sciences
We used plants as an in vivo pathogenesis model for the identification of virulence factors of
the human opportunistic pathogen Pseudomonas aeruginosa. Nine of nine Tn phoA mutant …

ParE toxin encoded by the broad‐host‐range plasmid RK2 is an inhibitor of Escherichia coli gyrase

Y Jiang, J Pogliano, DR Helinski… - Molecular …, 2002 - Wiley Online Library
Broad‐host‐range plasmid RK2 encodes a post‐segregational killing system, parDE, which
contributes to the stable maintenance of this plasmid in Escherichia coli and many distantly …

Construction and use of a versatile set of broad-host-range cloning and expression vectors based on the RK2 replicon

JM Blatny, T Brautaset… - Applied and …, 1997 - Am Soc Microbiol
The plasmid vectors described in this report are derived from the broad-host-range RK2
replicon and can be maintained in many gram-negative bacterial species. The complete …