Pharmaceutical Nanoparticles Formation and Their Physico-Chemical and Biomedical Properties

TI Shabatina, YA Gromova, OI Vernaya, AV Soloviev… - Pharmaceuticals, 2024 - mdpi.com
The use of medicinal substances in nanosized forms (nanoforms, nanoparticles) allows the
therapeutic effectiveness of pharmaceutical preparations to be increased due to several …

[HTML][HTML] Solubilization techniques used for poorly water-soluble drugs

B Xie, Y Liu, X Li, P Yang, W He - Acta Pharmaceutica Sinica B, 2024 - Elsevier
Currently, about 40% of approved drugs and nearly 90% of drug candidates are poorly
water-soluble drugs. Low solubility reduces the likelihood that these drugs can be effectively …

Naringin processing using GAS antisolvent technique and in vivo applications

PV Oliveira, JL Dias, GSB Sakata, GPS Aguiar… - The Journal of …, 2024 - Elsevier
Naringin is a flavanone glycoside with various pharmacological activities, including
neuroprotective and antipsychotic-like effects. However, it has poor solubility in water and …

Coprecipitation of nicotinic acid in PVP by gas antisolvent technique using Box-Behnken design

M Silveira, PV Oliveira, EA Rebelatto, DA Mayer… - Journal of Molecular …, 2024 - Elsevier
Nicotinic acid is a water-soluble compound recognized in the medical field for its ability to
decrease low-density lipoprotein cholesterol levels. Additionally, nicotinic acid is used to …

Topical drug delivery of licorice flavonoids and their structure-affinity relationship with the porcine skin

Z Wang, HY Xu, Y Hu, Y Wu, Q Zeng, H Chen… - Journal of Drug Delivery …, 2024 - Elsevier
Traditional Chinese medicine (TCM) possesses a long history of clinical application in the
transdermal prescriptions, however, their transdermal mechanisms had not been clearly …

Formation of naringin and naringenin particles in supercritical medium and evaluation of biological activities in vitro and in vivo

PV Oliveira - 2024 - repositorio.ufsc.br
The flavonoids naringin and its derivative naringenin have several notable biological
properties, standing out for their anti-inflammatory, antioxidant, neuroprotective, anti …

Micronização e cocristalização de berberina utilizando o método gás antissolvente (GAS)

GSB Sakata - 2023 - repositorio.ufsc.br
A berberina, um composto amplamente empreendedor na fitoterapia, constitui o principal
componente em diversas plantas de uso tradicional na medicina chinesa. Demonstra …