BACKGROUND The human sperm cell is very well suited for proteomic studies, as it is
accessible, can be easily purified and is believed to be transcriptionally and translationally …

Although male factors account for approximately 50% of all infertility, the mechanisms
underlying their origin are unknown. Currently, clinicians rely primarily on semen analyses …

Capacitation is a remarkable process whereby spermatozoa prepare themselves for
engagement with the oocyte. Although the existence of this process has been appreciated …

Spermatozoa acquire fertilization potential during passage through a highly specialized
region of the extratesticular ductal system known as the epididymis. In the absence of de …

Declining fertility rates in both human and animals is a cause for concern. While many of the
infertility cases are due to known causes, idiopathic infertility is reported in 30% of the …

Varicocele is a common medical condition entangled with many controversies. Though it is
highly prevalent in men with infertility, still it marks its presence in males who do have …

Circular RNAs (circRNAs) are a large family of newly identified transcripts, and their
physiological roles and evolutionary significance require further characterization. Here, we …

STUDY QUESTION How does oxidative stress impact upon human sperm–egg interaction
and in particular the formation of zona pellucida-receptor complexes on the sperm surface …

The horse breeding industry relies upon optimal stallion fertility. Conventional sperm
assessments provide limited information regarding ejaculate quality and are not individually …

Sperm-zona pellucida (ZP) interaction, involving the binding of sperm surface ligands to
complementary carbohydrates of ZP, is the first direct gamete contact event crucial for …