All biomaterials, when implanted in vivo, elicit cellular and tissue responses. These
responses include the inflammatory and wound healing responses, foreign body reactions …

The diverse immunomodulatory properties of mesenchymal stem/stromal cells (MSCs) may
be exploited for treatment of a multitude of inflammatory conditions. MSCs have long been …

Tissue engineering applications commonly encompass the use of three-dimensional (3D)
scaffolds to provide a suitable microenvironment for the incorporation of cells or growth …

Macrophages are the dominant infiltrating cells that respond rapidly to biomaterial
implantation in soft and hard tissues. These cells and their fused morphologic variants …

Adult tissue-derived mesenchymal stem cells (MSCs) have demonstrated therapeutic
efficacy in treating diseases or repairing damaged tissues through mechanisms thought to …

Recent evidence suggests that mesenchymal stem cells (MSC) selectively proliferate to
tumors and contribute to the formation of tumor-associated stroma. The biological rationale …

Collagen-based resorbable barrier membranes have been increasingly utilized for Guided
Bone Regeneration (GBR), as an alternative to non-resorbable synthetic membranes that …

Tissue engineering and cell therapy require large-scale production of homogeneous
populations of lineage-restricted progenitor cells that easily can be induced to differentiate …

Recent evidence suggests that mesenchymal stem cells (MSC) selectively home to tumors,
where they contribute to the formation of tumor-associated stroma. This effect can be …

CD47 on red blood cells (RBCs) reportedly signals “self” by binding SIRPα on phagocytes,
at least in mice. Such interactions across and within species, from mouse to human, are not …