Trends in insulin resistance: insights into mechanisms and therapeutic strategy
M Li, X Chi, Y Wang, S Setrerrahmane… - Signal transduction and …, 2022 - nature.com
The centenary of insulin discovery represents an important opportunity to transform diabetes
from a fatal diagnosis into a medically manageable chronic condition. Insulin is a key …
from a fatal diagnosis into a medically manageable chronic condition. Insulin is a key …
Controversies in the pathogenesis, diagnosis and treatment of PCOS: focus on insulin resistance, inflammation, and hyperandrogenism
D Armanini, M Boscaro, L Bordin… - International journal of …, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is a heterogeneous and extremely common disease with
symptoms that vary with the age of the patient, typically characterized by hyperandrogenism …
symptoms that vary with the age of the patient, typically characterized by hyperandrogenism …
Genetic basis of polycystic ovary syndrome (PCOS): current perspectives
Polycystic ovary syndrome (PCOS) is a common infertility disorder affecting a significant
proportion of the global population. It is the main cause of anovulatory infertility in women …
proportion of the global population. It is the main cause of anovulatory infertility in women …
Hyperandrogenemia and insulin resistance: The chief culprit of polycystic ovary syndrome
J Wang, D Wu, H Guo, M Li - Life sciences, 2019 - Elsevier
Polycystic ovary syndrome (PCOS) is one of the most common systemic reproductive
endocrine diseases, which has a variety of effects on a woman's health. Because of the …
endocrine diseases, which has a variety of effects on a woman's health. Because of the …
Metabolic syndrome and PCOS: Pathogenesis and the role of metabolites
W Chen, Y Pang - Metabolites, 2021 - mdpi.com
Polycystic ovary syndrome (PCOS) is one of the most common endocrine diseases among
women of reproductive age and is associated with many metabolic manifestations, such as …
women of reproductive age and is associated with many metabolic manifestations, such as …
Ethnicity, obesity and the prevalence of impaired glucose tolerance and type 2 diabetes in PCOS: a systematic review and meta-regression
BACKGROUND Our prior meta-analyses demonstrated an increased prevalence of
impaired glucose tolerance (IGT) and type 2 diabetes mellitus (T2DM) with polycystic ovary …
impaired glucose tolerance (IGT) and type 2 diabetes mellitus (T2DM) with polycystic ovary …
Women with polycystic ovary syndrome have intrinsic insulin resistance on euglycaemic–hyperinsulaemic clamp
STUDY QUESTION What is the prevalence of insulin resistance (IR) and the contributions of
intrinsic and extrinsic IR in women diagnosed with polycystic ovary syndrome (PCOS) …
intrinsic and extrinsic IR in women diagnosed with polycystic ovary syndrome (PCOS) …
Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan
Polycystic ovary syndrome (PCOS) is of clinical and public health importance as it is very
common, affecting up to one in five women of reproductive age. It has significant and diverse …
common, affecting up to one in five women of reproductive age. It has significant and diverse …
Roles of oxidative stress in polycystic ovary syndrome and cancers
T Zuo, M Zhu, W Xu - Oxidative medicine and cellular longevity, 2016 - Wiley Online Library
Oxidative stress (OS) has received extensive attention in the last two decades, because of
the discovery that abnormal oxidation status was related to patients with chronic diseases …
the discovery that abnormal oxidation status was related to patients with chronic diseases …
Impaired glucose tolerance, type 2 diabetes and metabolic syndrome in polycystic ovary syndrome: a systematic review and meta-analysis
LJ Moran, ML Misso, RA Wild… - Human reproduction …, 2010 - academic.oup.com
BACKGROUND Polycystic ovary syndrome (PCOS) is a common condition in reproductive-
aged women associated with impaired glucose tolerance (IGT), type 2 diabetes mellitus …
aged women associated with impaired glucose tolerance (IGT), type 2 diabetes mellitus …