Olfactory dysfunction in neurodegenerative diseases

C Marin, D Vilas, C Langdon, I Alobid… - Current allergy and …, 2018 - Springer
Abstract Purpose of Review The sense of smell is today one of the focuses of interest in
aging and neurodegenerative disease research. In several neurodegenerative diseases …

[HTML][HTML] Olfactory neuropathology in Alzheimer's disease: a sign of ongoing neurodegeneration

G Son, A Jahanshahi, SJ Yoo, JT Boonstra… - BMB …, 2021 - ncbi.nlm.nih.gov
Olfactory neuropathology is a cause of olfactory loss in Alzheimer's disease (AD). Olfactory
dysfunction is also associated with memory and cognitive dysfunction and is an incidental …

Olfactory dysfunction in Alzheimer's disease Systematic review and meta-analysis

MM Silva, PBS Mercer, MCZ Witt… - Dementia & …, 2018 - SciELO Brasil
Abstract Alzheimer's disease (AD), a neurodegenerative condition, is one of the most
prevalent kinds of dementia, whose frequency doubles for every 5 years of age in elderly …

Re-thinking the etiological framework of neurodegeneration

X Castillo, S Castro-Obregón… - Frontiers in …, 2019 - frontiersin.org
Neurodegenerative diseases are among the leading causes of disability and death
worldwide. The disease-related socioeconomic burden is expected to increase with the …

[PDF][PDF] Oxidative stress in Alzheimer disease as a target for therapy

M Pohanka - Bratisl. Lek. Listy, 2018 - researchgate.net
In the recent time, neurodegenerative disorders like Alzheimer disease were recognized for
their significant role in the current healthcare because of their growing incidence and costs …

Alzheimer's disease: what can we learn from the peripheral olfactory system?

M Dibattista, S Pifferi, A Menini, J Reisert - Frontiers in Neuroscience, 2020 - frontiersin.org
The sense of smell has been shown to deteriorate in patients with some neurodegenerative
disorders. In Parkinson's disease (PD) and Alzheimer's disease (AD), decreased ability to …

Longitudinal profiling of oligomeric Aβ in human nasal discharge reflecting cognitive decline in probable Alzheimer's disease

SJ Yoo, G Son, J Bae, SY Kim, YK Yoo, D Park… - Scientific Reports, 2020 - nature.com
Despite clinical evidence indicating a close relationship between olfactory dysfunction and
Alzheimer's disease (AD), further investigations are warranted to determine the diagnostic …

Region-specific amyloid-β accumulation in the olfactory system influences olfactory sensory neuronal dysfunction in 5xFAD mice

G Son, SJ Yoo, S Kang, A Rasheed, DH Jung… - Alzheimer's Research & …, 2021 - Springer
Abstract Background Hyposmia in Alzheimer's disease (AD) is a typical early symptom
according to numerous previous clinical studies. Although amyloid-β (Aβ), which is one of …

The nasal lymphatic route of CSF outflow: implications for neurodegenerative disease diagnosis and monitoring

J Chae, M Choi, J Choi, SJ Yoo - Animal Cells and Systems, 2024 - Taylor & Francis
Cerebrospinal fluid (CSF) plays a crucial role in the brain's lymphatics as it traverses the
central nervous system (CNS). Its primary function is to facilitate the outward transport of …

Is there a shared etiology of olfactory impairments in normal aging and neurodegenerative disease?

M Parvand, CH Rankin - Journal of Alzheimer's Disease, 2020 - content.iospress.com
As we age, our olfactory function declines. In addition to occurring in normal aging, more
rapid decrement of olfactory decline has been associated with several neurodegenerative …