Nerve blocks improve postoperative analgesia, but their benefits may be short-lived. This
quantitative review examines whether perineural dexmedetomidine as a local anaesthetic …

Background. Dexmedetomidine has been proposed as a perineural local anaesthetic (LA)
adjunct to prolong peripheral nerve block duration; however, results from our previous meta …

Now in its 7th edition, this popular, must-have text remains the only encyclopedic resource
for veterinary internal medical problems. The internationally acclaimed" gold standard" offers …

BACKGROUND AND OBJECTIVES: We evaluated the effect of adding dexmedetomidine to
levobupivacaine for axillary brachial plexus blockade. The primary endpoints were the onset …

The authors concluded that adding clonidine to intermediate or long-acting local
anaesthetics for single-shot peripheral nerve or plexus blocks prolonged duration of …

Background: We compared the effects of adding dexmedetomidine to a 30 ml solution of
0.325% bupivacaine in supraclavicular brachial plexus block. Onset and duration of sensory …

Introduction: Supraclavicular brachial plexus block provides safe, effective, low cost
anaesthesia with good postoperative analgesia. This study was conducted to compare the …

BACKGROUND: Central mechanisms have been proposed to explain the prolongation of
effect reported with the off-label use of dexmedetomidine as an adjuvant in local anesthetic …

BACKGROUND: Although several studies have described effects of dexmedetomidine on
peripheral nerve blocks, to date there is limited knowledge available on the impact of …

Backgroundα2-Adrenoceptor agonists administered into the intrathecal and epidural space
have been found to be effective in the treatment of chronic pain. Moreover, it was shown that …