UK recommendations for HER2 assessment in breast cancer: an update

EA Rakha, PH Tan, C Quinn, E Provenzano… - Journal of clinical …, 2023 - jcp.bmj.com
The last UK breast cancer (BC) human epidermal growth factor receptor 2 (HER2) testing
guideline recommendations were published in 2015. Since then, new data and therapeutic …

Update on the use of molecular subtyping in breast cancer

TJ Lawton - Advances in Anatomic Pathology, 2023 - journals.lww.com
The standard of care for invasive cancers of the breast has been and continues to be to
evaluate them for breast prognostic markers: estrogen receptor, progesterone receptor, and …

[HTML][HTML] HSF1 Inhibits Antitumor Immune Activity in Breast Cancer by Suppressing CCL5 to Block CD8+ T-cell Recruitment

C Jacobs, S Shah, WC Lu, H Ray, J Wang… - Cancer Research, 2024 - AACR
Abstract Heat shock factor 1 (HSF1) is a stress-responsive transcription factor that promotes
cancer cell malignancy. To provide a better understanding of the biological processes …

[HTML][HTML] Prospective study of a diabetes risk reduction diet and the risk of breast cancer

JH Kang, C Peng, JJ Rhee, MS Farvid… - The American journal of …, 2020 - Elsevier
Background Hyperinsulinemia and higher insulin-like growth factors may increase breast
cancer risk. We evaluated a diabetes risk reduction diet (DRRD) and breast cancer risk …

Branched-chain amino acids and risk of breast cancer

OA Zeleznik, R Balasubramanian, Y Ren… - JNCI cancer …, 2021 - academic.oup.com
Background Circulating branched-chain amino acid (BCAA) levels reflect metabolic health
and dietary intake. However, associations with breast cancer are unclear. Methods We …

Identification, characterization, and prognosis investigation of pivotal genes shared in different stages of breast cancer

F Rommasi - Scientific Reports, 2023 - nature.com
One of the leading causes of death (20.1 per 100,000 women per year), breast cancer is the
most prevalent cancer in females. Statistically, 95% of breast cancer are categorized as …

Comparison of clinical subtypes of breast cancer within the Claudin-low molecular cluster reveals distinct phenotypes

IA Voutsadakis - Cancers, 2023 - mdpi.com
Simple Summary Breast cancer is not one homogeneous disease, but it includes many
subtypes that are identified in the clinical and research setting. The claudin-low subtype is a …

Investigation of the role of PUFA metabolism in breast cancer using a rank-based random forest algorithm

MV Guryleva, DD Penzar, DV Chistyakov, AA Mironov… - Cancers, 2022 - mdpi.com
Simple Summary Polyunsaturated fatty acids (PUFAs) and their derivatives, oxylipins, are a
constant focus of cancer research due to the relationship between cancer and processes of …

Intrinsic subtypes in Ethiopian breast cancer patient

Z Desalegn, M Yohannes, M Porsch… - Breast Cancer Research …, 2022 - Springer
Purpose The recent development of multi-gene assays for gene expression profiling has
contributed significantly to the understanding of the clinically and biologically …

[HTML][HTML] Molecular subtyping improves breast cancer diagnosis in the Copenhagen Breast Cancer Genomics Study

T Berg, MB Jensen, A Celik, ML Talman, MA Misiakou… - JCI insight, 2024 - ncbi.nlm.nih.gov
BACKGROUND Intrinsic molecular subtypes define distinct biological breast cancers and
can be used to further improve diagnosis and risk allocation. METHODS The Copenhagen …