Autophagy is a core molecular pathway for the preservation of cellular and organismal
homeostasis. Pharmacological and genetic interventions impairing autophagy responses …

The term autophagy encompasses different pathways that route cytoplasmic material to
lysosomes for degradation and includes macroautophagy, chaperone-mediated autophagy …

Autophagy is a conserved pathway that delivers cytoplasmic contents to the lysosome for
degradation. Here we consider its roles in neuronal health and disease. We review …

Autophagy is an essential cellular mechanism which plays “housekeeping” role in normal
physiological processes including removing of long lived, aggregated and misfolded …

Macroautophagy is a conserved catabolic process observed in all eukaryotic cells, during
which selected cellular components are transported to and broken down within lysosomes …

Macroautophagy (autophagy) is a highly conserved intracellular degradation system that is
essential for homeostasis in eukaryotic cells. Due to the wide variety of the cytoplasmic …

Autophagy is a conserved intracellular pathway that delivers cytoplasmic contents to
lysosomes for degradation via double-membrane autophagosomes. Autophagy substrates …

Mitophagy is a cellular quality control pathway in which the E3 ubiquitin ligase parkin targets
damaged mitochondria for degradation by autophagosomes. We examined the role of …

Autoantibodies against nucleic acids and excessive type I interferon (IFN) are hallmarks of
human systemic lupus erythematosus (SLE). We previously reported that SLE neutrophils …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …