The surprising discovery that the diatomic gas nitric oxide (NO) is generated by mammalian
cells and serves to regulate a multitude of physiological processes has continued to …

Acute ischemic stroke is a common cause of morbidity and mortality worldwide.
Thrombolysis with recombinant tissue plasminogen activator and endovascular …

During the past two decades, nitric oxide (NO) has been recognized as one of the most
versatile players in the immune system. It is involved in the pathogenesis and control of …

Light-emitting diode photobiomodulation is the newest category of nonthermal light
therapies to find its way to the dermatologic armamentarium. In this article, we briefly review …

The physiological role of nitric oxide (NO) in the maintenance of vascular tone, in synaptic
transmission and in cellular defence is now firmly established. Recent evidence indicates …

Cells exposed to low oxygen concentrations respond by initiating defense mechanisms,
including the stabilization of hypoxia-inducible factor (HIF) 1α, a transcription factor that …

Following stimulation of NMDA receptors, neurons transiently synthesize nitric oxide (NO) in
a calcium/calmodulin‐dependent manner through the activation of neuronal NO synthase …

▪ Abstract Nitric oxide (NO) is a small, diffusible, lipophilic free radical gas that mediates
significant and diverse signaling functions in nearly every organ system in the body. The …

NO or its derivatives (reactive nitrogen species: RNS) inhibit mitochondrial respiration in two
different ways:(i) an acute, potent, and reversible inhibition of cytochrome oxidase by NO in …

Production of NO from arginine and molecular oxygen is a complex chemical reaction
unique to biology. Our understanding of the chemical and regulation mechanisms of the NO …