Salt-losing tubulopathies with secondary hyperaldosteronism (SLT) comprise a set of well-
defined inherited tubular disorders. Two segments along the distal nephron are primarily …

This Review outlines a terminology and classification of Bartter-like syndromes that is based
on the underlying causes of these inherited salt-losing tubulopathies and is, therefore, more …

At least three renal tubular segments are involved in the pathophysiology of salt-losing
tubulopathies (SLTs). Whether the pathogenesis starts either in the thick ascending limb of …

Prostaglandin E2 (PGE2) belongs to a family of biologically active lipids derived from the 20-
carbon essential fatty acids. Renal PGE2 is involved in the development of the kidney; it also …

Bartter syndrome is a hereditary disorder that has been characterized by the association of
hypokalemia, alkalosis, and the hypertrophy of the juxtaglomerular complex with secondary …

We conducted two studies to examine the hypothesis that lower urinary tract obstruction
induces excessive production of prostaglandin E2 (PGE2) in the bladder in young boys, with …

Great progress has been made in the last 15 years in the characterization and the
pathophysiological understanding of renal salt and water wasting associated with inherited …

Hyperprostaglandin E syndrome (HPS) is the antenatal variant of Bartter syndrome and
characterized by polyhydramnios and preterm delivery in the antenatal period and salt …

Auszug In wenigen Bereichen der Nephrologie sind in den letzten Jahren so viele
Fortschritte gemacht worden wie auf dem Gebiet der molekularbiologischen …

Eicosanoide sind natürliche hormonähnliche Substanzen, die in ihrer Struktur geringfügig
variieren und chemisch gesehen Derivate der Arachidonsäure sind. Prostaglandine und …