Recent developments in time-of-flight PET

S Vandenberghe, E Mikhaylova, E D'Hoe, P Mollet… - EJNMMI physics, 2016 - Springer
While the first time-of-flight (TOF)-positron emission tomography (PET) systems were already
built in the early 1980s, limited clinical studies were acquired on these scanners. PET was …

PET-MRI: a review of challenges and solutions in the development of integrated multimodality imaging

S Vandenberghe, PK Marsden - Physics in Medicine & Biology, 2015 - iopscience.iop.org
The integration of positron emission tomography (PET) and magnetic resonance imaging
(MRI) has been an ongoing research topic for the last 20 years. This paper gives an …

Roadmap toward the 10 ps time-of-flight PET challenge

P Lecoq, C Morel, JO Prior, D Visvikis… - Physics in Medicine …, 2020 - iopscience.iop.org
Since the seventies, positron emission tomography (PET) has become an invaluable
medical molecular imaging modality with an unprecedented sensitivity at the picomolar …

Attenuation correction synthesis for hybrid PET-MR scanners: application to brain studies

N Burgos, MJ Cardoso, K Thielemans… - IEEE transactions on …, 2014 - ieeexplore.ieee.org
Attenuation correction is an essential requirement for quantification of positron emission
tomography (PET) data. In PET/CT acquisition systems, attenuation maps are derived from …

[HTML][HTML] A multi-centre evaluation of eleven clinically feasible brain PET/MRI attenuation correction techniques using a large cohort of patients

CN Ladefoged, I Law, U Anazodo, KS Lawrence… - Neuroimage, 2017 - Elsevier
Aim To accurately quantify the radioactivity concentration measured by PET, emission data
need to be corrected for photon attenuation; however, the MRI signal cannot easily be …

Using domain knowledge for robust and generalizable deep learning-based CT-free PET attenuation and scatter correction

R Guo, S Xue, J Hu, H Sari, C Mingels… - Nature …, 2022 - nature.com
Despite the potential of deep learning (DL)-based methods in substituting CT-based PET
attenuation and scatter correction for CT-free PET imaging, a critical bottleneck is their …

A review of deep-learning-based approaches for attenuation correction in positron emission tomography

JS Lee - IEEE Transactions on Radiation and Plasma Medical …, 2020 - ieeexplore.ieee.org
Attenuation correction (AC) is essential for the generation of artifact-free and quantitatively
accurate positron emission tomography (PET) images. PET AC based on computed …

Generation of PET attenuation map for whole-body time-of-flight 18F-FDG PET/MRI using a deep neural network trained with simultaneously reconstructed activity and …

D Hwang, SK Kang, KY Kim, S Seo… - Journal of Nuclear …, 2019 - Soc Nuclear Med
We propose a new deep learning–based approach to provide more accurate whole-body
PET/MRI attenuation correction than is possible with the Dixon-based 4-segment method …

Improving the accuracy of simultaneously reconstructed activity and attenuation maps using deep learning

D Hwang, KY Kim, SK Kang, S Seo… - Journal of Nuclear …, 2018 - Soc Nuclear Med
Simultaneous reconstruction of activity and attenuation using the maximum-likelihood
reconstruction of activity and attenuation (MLAA) augmented by time-of-flight information is a …

Machine learning in PET: from photon detection to quantitative image reconstruction

K Gong, E Berg, SR Cherry, J Qi - Proceedings of the IEEE, 2019 - ieeexplore.ieee.org
Machine learning has found unique applications in nuclear medicine from photon detection
to quantitative image reconstruction. Although there have been impressive strides in …