Pancreatic cancer: a review of current treatment and novel therapies

HM Kolbeinsson, S Chandana, GP Wright… - Journal of Investigative …, 2023 - Taylor & Francis
Pancreatic cancer is one of the leading causes for cancer-related deaths in the United
States. Majority of patients present with unresectable or metastatic disease. For those that …

[HTML][HTML] Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes

A McGuigan, P Kelly, RC Turkington… - World journal of …, 2018 - ncbi.nlm.nih.gov
This review aims to outline the most up-to-date knowledge of pancreatic adenocarcinoma
risk, diagnostics, treatment and outcomes, while identifying gaps that aim to stimulate further …

Neoadjuvant chemoradiotherapy versus upfront surgery for resectable and borderline resectable pancreatic cancer: long-term results of the Dutch randomized …

E Versteijne, JL van Dam, M Suker… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE The benefit of neoadjuvant chemoradiotherapy in resectable and borderline
resectable pancreatic cancer remains controversial. Initial results of the PREOPANC trial …

Preoperative chemoradiotherapy versus immediate surgery for resectable and borderline resectable pancreatic cancer: results of the Dutch randomized phase III …

E Versteijne, M Suker, K Groothuis… - Journal of clinical …, 2020 - ascopubs.org
PURPOSE Preoperative chemoradiotherapy may improve the radical resection rate for
resectable or borderline resectable pancreatic cancer, but the overall benefit is unproven …

[HTML][HTML] Neoadjuvant therapy or upfront surgery for resectable and borderline resectable pancreatic cancer: a meta-analysis of randomised controlled trials

JL van Dam, QP Janssen, MG Besselink… - European Journal of …, 2022 - Elsevier
Introduction Neoadjuvant therapy may improve survival compared with upfront surgery in
patients with resectable and borderline resectable pancreatic cancer, but high-quality …

Optimizing the outcomes of pancreatic cancer surgery

O Strobel, J Neoptolemos, D Jaeger… - Nature reviews Clinical …, 2019 - nature.com
Pancreatic cancer is likely to become the second most frequent cause of cancer-associated
mortality within the next decade. Surgical resection with adjuvant systemic chemotherapy …

Randomized phase II/III trial of neoadjuvant chemotherapy with gemcitabine and S-1 versus upfront surgery for resectable pancreatic cancer (Prep-02/JSAP05)

F Motoi, T Kosuge, H Ueno, H Yamaue… - Japanese journal of …, 2019 - academic.oup.com
A randomized, controlled trial has begun to compare neoadjuvant chemotherapy using
gemcitabine and S-1 with upfront surgery for patients planned resection of pancreatic …

An update on treatment options for pancreatic adenocarcinoma

A Lambert, L Schwarz, I Borbath… - … in medical oncology, 2019 - journals.sagepub.com
Pancreatic cancer is one of the most lethal solid organ tumors. Due to the rising incidence,
late diagnosis, and limited treatment options, it is expected to be the second leading cause …

Pancreatic cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆

T Conroy, P Pfeiffer, V Vilgrain, A Lamarca… - Annals of …, 2023 - annalsofoncology.org
The opportunity to detect pancreatic cancer (PC) when potentially curable depends on early
diagnosis and an ability to identify and screen high-risk populations before symptoms arise …

Neoadjuvant FOLFIRINOX in patients with borderline resectable pancreatic cancer: a systematic review and patient-level meta-analysis

QP Janssen, S Buettner, M Suker… - JNCI: Journal of the …, 2019 - academic.oup.com
Background FOLFIRINOX is a standard treatment for metastatic pancreatic cancer patients.
The effectiveness of neoadjuvant FOLFIRINOX in patients with borderline resectable …