Advances in cancer biology over the past decades have revealed that metabolic adaptation
of cancer cells is an essential aspect of tumorigenesis. However, recent insights into tumour …

Cholesterol remains a vital molecule required for life; however, increasing evidence exists
implicating cholesterol in cancer development and progression. Numerous studies …

Aim: Adipose tissue (AT) dysfunction that occurs in both obesity and lipodystrophy is
associated with the development of cardiomyopathy. However, it is unclear how …

Viral infections attract more and more attention, especially after the emergence of novel
zoonotic coronaviruses and the monkeypox virus over the last 2 decades. Research on …

The flow of electrons in the mitochondrial electron transport chain (ETC) supports
multifaceted biosynthetic, bioenergetic, and signaling functions in mammalian cells. As …

The non-physiological nutrient levels found in traditional culture media have been shown to
affect numerous aspects of cancer cell physiology, including how cells respond to certain …

Ewing sarcoma (EwS) cell line culture largely relies on standard techniques, which do not
recapitulate physiological conditions. Here, we report on a physiologically improved …

Standard cell culture conditions do not mimic the physiological environment of cancer cells.
Traditional culture media contain metabolites at concentrations that far exceed conditions …