Brain-derived neurotrophic factor (BDNF) is a neuropeptide that plays numerous important
roles in synaptic development and plasticity. While its importance in fundamental physiology …

During the past decade, research has revealed that the vast community of micro-organisms
that inhabit the gut—known as the gut microbiota—is intricately linked to human health and …

Atrophy of neurons in the prefrontal cortex (PFC) plays a key role in the pathophysiology of
depression and related disorders. The ability to promote both structural and functional …

Major depressive disorder is a debilitating disorder affecting millions of people each year.
Brain-derived neurotrophic factor (BDNF) and inflammation are two prominent biologic risk …

Depression is the most prevalent and among the most debilitating of psychiatric disorders.
The precise neurobiology of this illness is unknown. Several lines of evidence suggest that …

Abstract According to the World Health Organization, two billion people will be aged 60
years or older by 2050. Aging is a major risk factor for a number of neurodegenerative …

Abstract Alzheimer's Disease (AD), the most prevalent neurodegenerative disease of aging,
affects one in eight older Americans. Nearly all drug treatments tested for AD today have …

Flavones have antioxidant, anti-proliferative, anti-tumor, anti-microbial, estrogenic, acetyl
cholinesterase, anti-inflammatory activities and are also used in cancer, cardiovascular …

Motivational and motor deficits are common in patients with depression and other psychiatric
disorders, and are related to symptoms of anhedonia and motor retardation. These deficits in …

Brain derived neurotrophic factor (BDNF) is the most prevalent growth factor in the central
nervous system (CNS). It is essential for the development of the CNS and for neuronal …