Clinical biology of the pituitary adenoma

S Melmed, UB Kaiser, MB Lopes, J Bertherat… - Endocrine …, 2022 - academic.oup.com
All endocrine glands are susceptible to neoplastic growth, yet the health consequences of
these neoplasms differ between endocrine tissues. Pituitary neoplasms are highly prevalent …

Aggressive pituitary tumours and pituitary carcinomas

G Raverot, MD Ilie, H Lasolle, V Amodru… - Nature Reviews …, 2021 - nature.com
Although usually benign, anterior pituitary tumours occasionally exhibit aggressive
behaviour, with invasion of surrounding tissues, rapid growth, resistance to conventional …

Integrated proteogenomic characterization across major histological types of pituitary neuroendocrine tumors

F Zhang, Q Zhang, J Zhu, B Yao, C Ma, N Qiao, S He… - Cell Research, 2022 - nature.com
Pituitary neuroendocrine tumor (PitNET) is one of the most common intracranial tumors. Due
to its extensive tumor heterogeneity and the lack of high-quality tissues for biomarker …

[HTML][HTML] Single nucleus transcriptome and chromatin accessibility of postmortem human pituitaries reveal diverse stem cell regulatory mechanisms

Z Zhang, M Zamojski, GR Smith, TL Willis, V Yianni… - Cell reports, 2022 - cell.com
Despite their importance in tissue homeostasis and renewal, human pituitary stem cells
(PSCs) are incompletely characterized. We describe a human single nucleus RNA-seq and …

Classification of neuroendocrine neoplasms: lights and shadows

S La Rosa, S Uccella - Reviews in endocrine and metabolic disorders, 2021 - Springer
Neuroendocrine neoplasms (NENs) are a heterogeneous group of neoplastic proliferations
showing different morphological features, immunophenotype, molecular background …

Tumor type detection in brain MR images of the deep model developed using hypercolumn technique, attention modules, and residual blocks

M Toğaçar, B Ergen, Z Cömert - Medical & Biological Engineering & …, 2021 - Springer
Brain cancer is a disease caused by the growth of abnormal aggressive cells in the brain
outside of normal cells. Symptoms and diagnosis of brain cancer cases are producing more …

Overview of the 2022 WHO classification of pituitary adenomas/pituitary neuroendocrine tumors: clinical practices, controversies, and perspectives

X Wan, J Chen, J Wang, Y Liu, K Shu, T Lei - Current Medical Science, 2022 - Springer
The latest edition of the WHO classification of the central nervous system was published in
2021. This review summarizes the major revisions to the classification of anterior pituitary …

An overview of circulating biomarkers in neuroendocrine neoplasms: a clinical guide

M Bevere, F Masetto, ME Carazzolo, A Bettega… - Diagnostics, 2023 - mdpi.com
Neuroendocrine neoplasms (NENs) are a heterogeneous group of diseases that are
characterized by different behavior and clinical manifestations. The diagnosis and …

Single-cell sequencing identifies differentiation-related markers for molecular classification and recurrence prediction of PitNET

Q Zhang, B Yao, X Long, Z Chen, M He, Y Wu… - Cell Reports …, 2023 - cell.com
Pituitary neuroendocrine tumor (PitNET) is one of the most common intracranial tumors with
variable recurrence rate. Currently, the recurrence prediction is unsatisfying and can be …

Single-cell transcriptomic analysis reveals tumor cell heterogeneity and immune microenvironment features of pituitary neuroendocrine tumors

N Yan, W Xie, D Wang, Q Fang, J Guo, Y Chen, X Li… - Genome Medicine, 2024 - Springer
Abstract Background Pituitary neuroendocrine tumors (PitNETs) are one of the most
common types of intracranial tumors. Currently, the cellular characteristics of normal pituitary …