Application of machine learning for high-throughput tumor marker screening

X Fu, W Ma, Q Zuo, Y Qi, S Zhang, Y Zhao - Life Sciences, 2024 - Elsevier
High-throughput sequencing and multiomics technologies have allowed increasing
numbers of biomarkers to be mined and used for disease diagnosis, risk stratification …

Imaging and AI based chromatin biomarkers for diagnosis and therapy evaluation from liquid biopsies

K Challa, D Paysan, D Leiser, N Sauder… - NPJ precision …, 2023 - nature.com
Multiple genomic and proteomic studies have suggested that peripheral blood mononuclear
cells (PBMCs) respond to tumor secretomes and thus could provide possible avenues for …

UGT8 在胃癌组织中的表达及对胃癌细胞转移的调控作用

何旭旭, 赵萌, 杨一群, 左芦根, 耿志军, 葛思堂… - 中华全科医学, 2023 - zhqkyx.net
目的研究尿苷二磷酸糖基转移酶8 (UGT8) 在胃癌组织中的表达情况, 并探讨其与患者远期预后
的关系及对胃癌细胞转移的调控作用. 方法纳入分析2013 年12 月-2016 年10 …

The impact of the tumor microenvironment on the survival of penile cancer patients

S Lohse, JN Mink, L Eckhart, MC Hans, L Jusufi… - Scientific reports, 2024 - nature.com
PeCa is a rare entity with rising incidence rates due to increased infections with human
papillomaviruses (HPV). The distinct subtypes of PeCa with an individual pathogenesis …

PanCanSurvPlot: a large-scale pan-cancer survival analysis web application

A Lin, H Yang, Y Shi, Q Cheng, Z Liu, J Zhang, P Luo - BioRxiv, 2022 - biorxiv.org
The identification of reliable tumor prognostic markers can help clinicians and researchers
predict tumor development and patient survival outcomes more accurately, which plays a …

Mapping Conformational Changes in the Saliva Proteome Potentially Associated with Oral Cancer Aggressiveness

DC Granato, CM Carnielli, LD Trino… - Journal of Proteome …, 2024 - ACS Publications
Diverse proteomics-based strategies have been applied to saliva to quantitatively identify
diagnostic and prognostic targets for oral cancer. Considering that these targets may be …

[HTML][HTML] The tumor cell killing capacity of head and neck cancer patient-derived neutrophils depends on tumor stage, gender and the antibody isotype

A Valcenko, A Zwick, L Schneider, M Linxweiler… - Oral Oncology, 2024 - Elsevier
Neutrophils play a crucial role in the tumor microenvironment (TME) of head and neck
squamous cell carcinomas (HNSCC) and significantly influence treatment outcomes …

Single-cell RNA profiling of ocular adnexal sebaceous carcinoma reveals a complex tumor microenvironment and identifies new biomarkers

MG Zhang, RA Gallo, CH Tan, M Camacho… - American journal of …, 2025 - Elsevier
Purpose Ocular adnexal sebaceous carcinoma (OaSC) is an aggressive malignancy that
often necessitates orbital exenteration. Its tumor composition and transcriptional profile …

Salivary proteins offer insights into keratinocyte death during aphthous stomatitis. A case-crossover study

C Cofré-Leiva, PA Camargo-Ayala, A Vergara-Pérez… - BMC Oral Health, 2023 - Springer
Background The death of oral keratinocytes is a crucial step in the emergence of recurrent
aphthous stomatitis (RAS, also known as aphthae or aphthous ulcers). Since there are no …

Engineering Dimeric EGFR-directed IgA Antibodies Reveals a Central Role of CD147 during Neutrophil-mediated Tumor Cell Killing of Head and Neck Squamous …

A Zwick, FL Braun, LJ Weber, M Linder… - The Journal of …, 2024 - journals.aai.org
Abstract Human IgA Abs engage neutrophils for cancer immunotherapy more effectively
than IgG Abs. Previous studies demonstrated that engineering approaches improved …