Abstract In 2010, the World Health Organization (WHO) established an indoor air quality
guideline for short-and long-term exposures to formaldehyde (FA) of 0.1 mg/m 3 (0.08 ppm) …

Genotoxicity data are mainly interpreted in a qualitative way, which typically results in a
binary classification of chemical entities. For more than a decade, there has been a …

With the release of the landmark report Toxicity Testing in the 21st Century: A Vision and a
Strategy, the US National Academy of Sciences, in 2007, precipitated a major change in the …

Hayes' Principles and Methods of Toxicology has long been established as a reliable and
informative reference for the concepts, methodologies, and assessments integral to …

An important goal in toxicology is the development of new ways to increase the speed,
accuracy, and applicability of chemical hazard and risk assessment approaches. A …

A quantitative adverse outcome pathway (qAOP) consists of one or more biologically based,
computational models describing key event relationships linking a molecular initiating event …

The nose is a very complex organ with multiple functions that include not only olfaction, but
also the conditioning (eg, humidifying, warming, and filtering) of inhaled air. The nose is also …

Formaldehyde is a widely used high production chemical that is also released as a
byproduct of combustion, off-gassing of various building products, and as a fixative for …

Formaldehyde is a well-studied chemical and effects from inhalation exposures have been
extensively characterized in numerous controlled studies with human volunteers, including …

Formaldehyde is a ubiquitous indoor air pollutant that is classified as “Carcinogenic to
humans (Group 1)”(IARC, Formaldehyde, 2-butoxyethanol and 1-tert-butoxypropanol-2-ol …