Most Escherichia coli strains live harmlessly in the intestines and rarely cause disease in
healthy individuals. Nonetheless, a number of pathogenic strains can cause diarrhea or …

Oral Diseases (2010) 16, 729–739 The colonization of oral surfaces by micro‐organisms
occurs in a characteristic sequence of stages, each of which is potentially amenable to …

Mucosal immune responses are the first‐line defensive mechanisms against a variety of
infections. Therefore, immunizations of mucosal surfaces from which majority of infectious …

Mucosal administration of Ags induces specific Abs in external secretions and systemic
unresponsiveness termed oral or mucosal tolerance. The dominant response depends on …

The heat-labile enterotoxins expressed by Vibrio cholerae (cholera toxin) and Escherichia
coli (LT-I, LT-IIa and LT-IIb) are potent systemic and mucosal adjuvants. Coadministration of …

Lactic acid bacteria (LAB) are Gram-positive, acid-tolerant bacteria that have long been
used in food fermentation and are generally recognized as safe (GRAS). LAB are a part of a …

The heat-labile toxins (LT) produced by enterotoxigenic Escherichia coli display adjuvant
effects to coadministered antigens, leading to enhanced production of serum antibodies …

We have previously demonstrated the full-length gonococcal transferrin binding proteins
(TbpA and TbpB) to be promising antigens in the development of a protective vaccine …

Escherichia coli and Vibrio cholerae produce structurally related AB5-type heat-labile
enterotoxins, which are classified into two major types. The Type I subfamily includes …

Objective: To devise a simple clinical scoring system, using age of patients and laboratory
data available on admission, to predict in‐hospital mortality of unselected medical and …