Osteosarcoma (OS) is the most frequent primary bone cancer in children and adolescents
and the third most frequent in adults. Many inherited germline mutations are responsible for …

Osteosarcoma (OS) is the most common type of primary bone tumor in children and
adolescents and has been associated with a high degree of malignancy, early metastasis …

Objective Osteosarcoma (OS) is a common bone malignancy with poor prognosis. We
aimed to investigate the relationship between cuproptosis-related lncRNAs (CRLncs) and …

Importance Osteosarcoma, the most common malignant bone tumor in children and
adolescents, occurs in a high number of cancer predisposition syndromes that are defined …

Osteosarcoma is the predominant form of bone cancer, affecting mostly adolescents. Recent
progress made in molecular genetic studies of osteosarcoma has changed our view on the …

Osteosarcoma is a primary bone malignancy with a particularly high incidence rate in
children and adolescents relative to other age groups. The etiology of this often aggressive …

Abstract The Osteosarcoma Surveillance Study, an ongoing 15‐year surveillance study
initiated in 2003, is a postmarketing commitment to the United States (US) Food and Drug …

Rare hereditary disorders provide unequivocal evidence of the importance of genes in
human disease pathogenesis. Familial syndromes that predispose to osteosarcomagenesis …

Osteosarcoma is the most common primary bone malignancy of adolescents and young
adults. To better understand the genetic etiology of osteosarcoma, we performed a …

Background Osteosarcoma (OS) is a malignant tumor mainly occurring in young people.
Due to the limited effective therapeutic strategies, OS patients cannot achieve further …