Background Depressive disorders are common in children and adolescents.
Antidepressants, psychotherapies, and their combination are often used in routine clinical …

Suicide is a complex public health problem of global importance. Suicidal behaviour differs
between sexes, age groups, geographic regions, and sociopolitical settings, and variably …

OBJECTIVES: Suicide ideation (SI) and suicide attempts (SAs) have been reported as
increasing among US children over the last decade. We examined trends in emergency and …

Background Self‐harm (SH; intentional self‐poisoning or self‐injury regardless of degree of
suicidal intent or other types of motivation) is a growing problem in most countries, often …

The number of adolescent deaths that result from suicide in the United States had been
increasing dramatically during recent decades until 1990, when it began to decrease …

Introduction Selective serotonin reuptake inhibitors (SSRIs) and, to a lesser extent, serotonin‐
norepinephrine reuptake inhibitors (SNRIs) are the cornerstone of pharmacotherapy for …

Interrupted time series (ITS) is a powerful and increasingly popular design for evaluating
public health and health service interventions. The design involves analyzing trends in the …

Background Major depressive disorders have a significant impact on children and
adolescents, including on educational and vocational outcomes, interpersonal relationships …

Suicide ranks among the leading causes of death around the world and takes a heavy
emotional and public health toll on most societies. Both distal and proximal factors contribute …

Background Depression increases the risk of a range of adverse outcomes including
suicide, premature mortality, and self-harm, but associations with violent crime remain …