Microfluidics for studying metastatic patterns of lung cancer

M Ruzycka, MR Cimpan, I Rios-Mondragon… - Journal of …, 2019 - Springer
The incidence of lung cancer continues to rise worldwide. Because the aggressive
metastasis of lung cancer cells is the major drawback of successful therapies, the crucial …

[PDF][PDF] Organ-on-a-chip platforms for drug delivery and cell characterization: A review

Z Wang, R Samanipour, KI Koo, K Kim - Sens. Mater, 2015 - researchgate.net
Developments in micro-and nanofluidic technologies have led to new kinds of cell culture
and screening systems that are collectively termed organ-on-a-chip systems. Organ-on-a …

SCHEEPDOG: programming electric cues to dynamically herd large-scale cell migration

TJ Zajdel, G Shim, L Wang, A Rossello-Martinez… - Cell systems, 2020 - cell.com
Directed cell migration is critical across biological processes spanning healing to cancer
invasion, yet no existing tools allow real-time interactive guidance over such migration. We …

Advances in pulmonary therapy and drug development: Lung tissue engineering to lung-on-a-chip

A Doryab, G Amoabediny, A Salehi-Najafabadi - Biotechnology advances, 2016 - Elsevier
Lung disease is one of the major causes of death, and the rate of pulmonary diseases has
been increasing for decades. Although lung transplantation is the only treatment for majority …

Pulsed DC electric field–induced differentiation of cortical neural precursor cells

HF Chang, YS Lee, TK Tang, JY Cheng - PloS one, 2016 - journals.plos.org
We report the differentiation of neural stem and progenitor cells solely induced by direct
current (DC) pulses stimulation. Neural stem and progenitor cells in the adult mammalian …

Active cell capturing for organ-on-a-chip systems: A review

M Bayareh - Biomedical Engineering/Biomedizinische Technik, 2022 - degruyter.com
Abstract Organ-on-a-chip (OOC) is an emerging technology that has been proposed as a
new powerful cell-based tool to imitate the pathophysiological environment of human …

Organ-on-a-chip platforms for drug screening and tissue engineering

Z Wang, R Samanipour, K Kim - Biomedical engineering: frontier research …, 2016 - Springer
Developments in micro-and nanofluidic technologies have led to new kinds of cell culture
and screening systems that are collectively termed organ-on-a-chip systems. Organ-on-a …

Studying electrotaxis in microfluidic devices

YS Sun - Sensors, 2017 - mdpi.com
Collective cell migration is important in various physiological processes such as
morphogenesis, cancer metastasis and cell regeneration. Such migration can be induced …

Correlation between cell migration and reactive oxygen species under electric field stimulation

SY Wu, HS Hou, YS Sun, JY Cheng, KY Lo - Biomicrofluidics, 2015 - pubs.aip.org
Cell migration is an essential process involved in the development and maintenance of
multicellular organisms. Electric fields (EFs) are one of the many physical and chemical …

Quantifying the roles of random motility and directed motility using advection-diffusion theory for a 3T3 fibroblast cell migration assay stimulated with an electric field

MJ Simpson, KY Lo, YS Sun - BMC Systems Biology, 2017 - Springer
Background Directed cell migration can be driven by a range of external stimuli, such as
spatial gradients of: chemical signals (chemotaxis); adhesion sites (haptotaxis); or …