Discovered in 1993, micoRNAs (miRNAs) are now recognized as one of the major
regulatory gene families in eukaryotes. To date, 24521 microRNAs have been discovered …

MicroRNAs (miRNAs) have emerged as key gene regulators in diverse biological pathways.
These small non-coding RNAs bind to target sequences in mRNAs, typically resulting in …

Background Non-alcoholic fatty liver disease (NAFLD) is a spectrum of disease ranging from
simple hepatic steatosis (NAFL) to non-alcoholic steatohepatitis (NASH) which may …

MicroRNAs are well known to mediate translational repression and mRNA degradation in
the cytoplasm. Various microRNAs have also been detected in membrane …

There is now compelling evidence that the complexity of higher organisms correlates with
the relative amount of non-coding RNA rather than the number of protein-coding genes …

MicroRNAs are small non‐coding RNA guide molecules that regulate gene expression via
association with effector complexes and sequence‐specific recognition of target sites on …

Introduction: MicroRNAs (miRNAs), which are evolutionarily conserved, and endogenous
non-coding RNAs, participate in the post-transcriptional regulation of eukaryotic genes. The …

The combined use of transcriptome and translatome as indicators of gene expression
profiles is usually more accurate than the use of transcriptomes alone, especially in cell …

MicroRNAs can promote translation of specific mRNAs in quiescent (G0) mammalian cells
and immature Xenopus laevis oocytes. We report that microRNA-mediated upregulation of …

The microRNA (miRNA)-mediated repression of protein synthesis in mammalian cells is a
reversible process. Target mRNAs with regulatory AU-rich elements (AREs) in their 3 …