Transformer for one stop interpretable cell type annotation

J Chen, H Xu, W Tao, Z Chen, Y Zhao… - Nature …, 2023 - nature.com
Consistent annotation transfer from reference dataset to query dataset is fundamental to the
development and reproducibility of single-cell research. Compared with traditional …

To transformers and beyond: large language models for the genome

ME Consens, C Dufault, M Wainberg, D Forster… - arXiv preprint arXiv …, 2023 - arxiv.org
In the rapidly evolving landscape of genomics, deep learning has emerged as a useful tool
for tackling complex computational challenges. This review focuses on the transformative …

Large language models in plant biology

HYI Lam, XE Ong, M Mutwil - Trends in Plant Science, 2024 - cell.com
Large language models (LLMs), such as ChatGPT, have taken the world by storm. However,
LLMs are not limited to human language and can be used to analyze sequential data, such …

Deep learning in single-cell analysis

D Molho, J Ding, W Tang, Z Li, H Wen, Y Wang… - ACM Transactions on …, 2024 - dl.acm.org
Single-cell technologies are revolutionizing the entire field of biology. The large volumes of
data generated by single-cell technologies are high dimensional, sparse, and …

The performance of deep generative models for learning joint embeddings of single-cell multi-omics data

E Brombacher, M Hackenberg, C Kreutz… - Frontiers in Molecular …, 2022 - frontiersin.org
Recent extensions of single-cell studies to multiple data modalities raise new questions
regarding experimental design. For example, the challenge of sparsity in single-omics data …

Proteomic alteration in the progression of multiple myeloma: A comprehensive review

NH Ismail, A Mussa, MJ Al-Khreisat, S Mohamed Yusoff… - Diagnostics, 2023 - mdpi.com
Multiple myeloma (MM) is an incurable hematologic malignancy. Most MM patients are
diagnosed at a late stage because the early symptoms of the disease can be uncertain and …

Machine learning in onco-pharmacogenomics: A path to precision medicine with many challenges

A Mondello, M Dal Bo, G Toffoli… - Frontiers in Pharmacology, 2024 - frontiersin.org
Over the past two decades, Next-Generation Sequencing (NGS) has revolutionized the
approach to cancer research. Applications of NGS include the identification of tumor specific …

Machine learning: a suitable method for biocatalysis

PS Sampaio, P Fernandes - Catalysts, 2023 - mdpi.com
Biocatalysis is currently a workhorse used to produce a wide array of compounds, from bulk
to fine chemicals, in a green and sustainable manner. The success of biocatalysis is largely …

Mapping Cell Atlases at the Single‐Cell Level

F Ye, J Wang, J Li, Y Mei, G Guo - Advanced Science, 2024 - Wiley Online Library
Recent advancements in single‐cell technologies have led to rapid developments in the
construction of cell atlases. These atlases have the potential to provide detailed information …

Deep learning in spatial transcriptomics: Learning from the next next-generation sequencing

AA Heydari, SS Sindi - Biophysics Reviews, 2023 - pubs.aip.org
Spatial transcriptomics (ST) technologies are rapidly becoming the extension of single-cell
RNA sequencing (scRNAseq), holding the potential of profiling gene expression at a single …