The molecular mechanisms by which vitamin D prevents insulin resistance and associated disorders

I Szymczak-Pajor, J Drzewoski, A Śliwińska - International journal of …, 2020 - mdpi.com
Numerous studies have shown that vitamin D deficiency is very common in modern societies
and is perceived as an important risk factor in the development of insulin resistance and …

Endothelial dysfunction in obesity-induced inflammation: molecular mechanisms and clinical implications

IK Kwaifa, H Bahari, YK Yong, SM Noor - Biomolecules, 2020 - mdpi.com
Obesity is characterized by the excessive deposition of fat that may interfere with the normal
metabolic process of the body. It is a chronic condition associated with various metabolic …

Multifaceted mechanisms of vascular calcification in aging

LA Pescatore, LF Gamarra… - … , thrombosis, and vascular …, 2019 - Am Heart Assoc
Approximately 20% of the world's population will be around or above 65 years of age by the
next decade. Out of these, 40% are suspected to have cardiovascular diseases as a cause …

Medial arterial calcification: a significant and independent contributor of peripheral artery disease

C St. Hilaire - Arteriosclerosis, thrombosis, and vascular biology, 2022 - Am Heart Assoc
Over 200 million individuals worldwide are estimated to have peripheral artery disease
(PAD). Although the term peripheral can refer to any outer branch of the vasculature, the …

Oxidative stress in vascular calcification

CT Hu, YD Shao, YZ Liu, X Xiao, ZB Cheng, SL Qu… - Clinica chimica acta, 2021 - Elsevier
Vascular calcification (VC), which is closely associated with significant mortality in
cardiovascular disease, chronic kidney disease (CKD), and/or diabetes mellitus, is …

Oxidative stress and vascular damage in the context of obesity: The hidden guest

E Martínez-Martínez, F V. Souza-Neto… - Antioxidants, 2021 - mdpi.com
The vascular system plays a central role in the transport of cells, oxygen and nutrients
between different regions of the body, depending on the needs, as well as of metabolic …

L-type calcium ion channel-mediated activation of autophagy in vascular smooth muscle cells via thonningianin A (TA) alleviates vascular calcification in type 2 …

J Shen, C Zhang, Y Liu, M Zhao, Q Wang, P Li… - European Journal of …, 2023 - Elsevier
Vascular calcification (VC) is associated with increased morbidity and mortality, especially
among people with type 2 diabetes mellitus (T2DM). The pathogenesis of vascular …

Açaí seed extract (ASE) rich in proanthocyanidins improves cardiovascular remodeling by increasing antioxidant response in obese high-fat diet-fed mice

BJ de Moraes Arnoso, FM Magliaccio… - Chemico-Biological …, 2022 - Elsevier
Obesity is recognized as an independent risk factor for cardiovascular diseases and is an
important contributor to cardiac mortality. Açaí seed extract (ASE), rich in proanthocyanidins …

Different metabolic phenotypes of obesity and risk of coronary artery calcium progression and incident cardiovascular disease events: The CARDIA Study

JW Gao, S You, ZY Liu, QY Hao, JF Wang… - … and Vascular Biology, 2022 - Am Heart Assoc
Background: To investigate whether obesity with or without metabolic syndrome is
prospectively associated with coronary artery calcium (CAC) progression and incident …

The role of vitamin D in modulating mesenchymal stem cells and endothelial progenitor cells for vascular calcification

YC Hou, CL Lu, CM Zheng, WC Liu, TH Yen… - International Journal of …, 2020 - mdpi.com
Vascular calcification, which involves the deposition of calcifying particles within the arterial
wall, is mediated by atherosclerosis, vascular smooth muscle cell osteoblastic changes …