Legionnaires' disease: update on diagnosis and treatment

D Viasus, V Gaia, C Manzur-Barbur… - Infectious Diseases and …, 2022 - Springer
Legionellosis is the infection caused by bacteria of the genus Legionella, including a non-
pneumonic influenza-like syndrome, and Legionnaires' disease is a more serious illness …

[HTML][HTML] Oral amoxicillin and amoxicillin–clavulanic acid: properties, indications and usage

A Huttner, J Bielicki, MN Clements… - Clinical Microbiology …, 2020 - Elsevier
Background Amoxicillin has been in use since the 1970s; it is the most widely used penicillin
both alone and in combination with the β-lactamase clavulanic acid. Objectives In this …

Diagnosis and treatment of adults with community-acquired pneumonia. An official clinical practice guideline of the American Thoracic Society and Infectious Diseases …

JP Metlay, GW Waterer, AC Long… - American journal of …, 2019 - atsjournals.org
Background: This document provides evidence-based clinical practice guidelines on the
management of adult patients with community-acquired pneumonia. Methods: A …

Discontinuing β-lactam treatment after 3 days for patients with community-acquired pneumonia in non-critical care wards (PTC): a double-blind, randomised, placebo …

A Dinh, J Ropers, C Duran, B Davido, L Deconinck… - The Lancet, 2021 - thelancet.com
Background Shortening the duration of antibiotic therapy for patients admitted to hospital
with community-acquired pneumonia should help reduce antibiotic consumption and thus …

Effect of 7 vs 14 days of antibiotic therapy on resolution of symptoms among afebrile men with urinary tract infection: a randomized clinical trial

DM Drekonja, B Trautner, C Amundson, M Kuskowski… - JaMa, 2021 - jamanetwork.com
Importance Determination of optimal treatment durations for common infectious diseases is
an important strategy to preserve antibiotic effectiveness. Objective To determine whether 7 …

Short-course antimicrobial therapy for pediatric community-acquired pneumonia: the SAFER randomized clinical trial

JM Pernica, S Harman, AJ Kam, R Carciumaru… - JAMA …, 2021 - jamanetwork.com
Importance Community-acquired pneumonia (CAP) is a common occurrence in childhood;
consequently, evidence-based recommendations for its treatment are required. Objective To …

Excess antibiotic treatment duration and adverse events in patients hospitalized with pneumonia: a multihospital cohort study

VM Vaughn, SA Flanders, A Snyder… - Annals of internal …, 2019 - acpjournals.org
Background: Randomized trials demonstrate no benefit from antibiotic treatment exceeding
the shortest effective duration. Objective: To examine predictors and outcomes associated …

[HTML][HTML] Estimating daily antibiotic harms: an umbrella review with individual study meta-analysis

J Curran, J Lo, V Leung, K Brown, KL Schwartz… - Clinical Microbiology …, 2022 - Elsevier
Background There is growing evidence supporting the efficacy of shorter courses of
antibiotic therapy for common infections. However, the risks of prolonged antibiotic duration …

The antibiotic course has had its day

MJ Llewelyn, JM Fitzpatrick, E Darwin, C Gorton, J Paul… - Bmj, 2017 - bmj.com
The antibiotic course has had its day | The BMJ Skip to main content Intended for healthcare
professionals Access provided by Google Indexer Subscribe My Account My email alerts BMA …

Antimicrobial-associated harm in critical care: a narrative review

N Arulkumaran, M Routledge, S Schlebusch… - Intensive care …, 2020 - Springer
The belief that, for the individual patient, the benefit of prompt and continued use of
antimicrobials outweighs any potential harm is a significant barrier to improved stewardship …