[HTML][HTML] Glutathione: A Samsonian life-sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation

CA Labarrere, GS Kassab - Frontiers in Nutrition, 2022 - frontiersin.org
Many local and systemic diseases especially diseases that are leading causes of death
globally like chronic obstructive pulmonary disease, atherosclerosis with ischemic heart …

Adjuvant physiochemistry and advanced nanotechnology for vaccine development

H Ren, W Jia, Y Xie, M Yu, Y Chen - Chemical Society Reviews, 2023 - pubs.rsc.org
Vaccines comprising innovative adjuvants are rapidly reaching advanced translational
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …

[HTML][HTML] Small molecule-based immunomodulators for cancer therapy

Y Wu, Z Yang, K Cheng, H Bi, J Chen - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Immunotherapy has led to a paradigm shift in the treatment of cancer. Current cancer
immunotherapies are mostly antibody-based, thus possessing advantages in regard to …

Toll-like receptor-mediated neuroinflammation: relevance for cognitive dysfunctions

S Squillace, D Salvemini - Trends in pharmacological sciences, 2022 - cell.com
Toll-like receptors (TLRs) are pattern recognition receptors (PRRs) with a well-documented
role in the innate and adaptive immune responses. Interestingly, TLR activation has also …

[HTML][HTML] Toll-like receptors and NLRP3 inflammasome-dependent pathways in Parkinson's disease: mechanisms and therapeutic implications

L Soraci, ME Gambuzza, L Biscetti, P Laganà… - Journal of …, 2023 - Springer
Parkinson's disease (PD) is a chronic progressive neurodegenerative disorder
characterized by motor and non-motor disturbances as a result of a complex and not fully …

[HTML][HTML] Identification of common molecular signatures of SARS-CoV-2 infection and its influence on acute kidney injury and chronic kidney disease

W Zhang, L Liu, X Xiao, H Zhou, Z Peng… - Frontiers in …, 2023 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the main cause of
COVID-19, causing hundreds of millions of confirmed cases and more than 18.2 million …

[HTML][HTML] Innate and adaptive responses of intratumoral immunotherapy with endosomal toll-like receptor agonists

FT Andón, S Leon, A Ummarino, E Redin, P Allavena… - Biomedicines, 2022 - mdpi.com
Toll-like receptors (TLRs) are natural initial triggers of innate and adaptive immune
responses. With the advent of cancer immunotherapy, nucleic acids engineered as ligands …

[HTML][HTML] Effect of CpG-oligonucleotide in enhancing recombinant herpes virus of turkey-laryngotracheitis vaccine-induced immune responses in one-day-old broiler …

C Gaghan, M Browning, AL Cortes, IM Gimeno… - Vaccines, 2023 - mdpi.com
Infectious laryngotracheitis (ILT) is an economically important disease of chickens. While the
recombinant vaccines can reduce clinical disease severity, the associated drawbacks are …

[HTML][HTML] Toll-like receptors in cardiac hypertrophy

Y Zhang, J Wu, E Dong, Z Wang, H Xiao - Frontiers in Cardiovascular …, 2023 - frontiersin.org
Toll-like receptors (TLRs) are a family of pattern recognition receptors (PRRs) that can
identify pathogen-associated molecular patterns (PAMPs) and damage-associated …

[HTML][HTML] Intraperitoneal metastasis of ovarian cancer: new insights on resident macrophages in the peritoneal cavity

T Miyamoto, B Murphy, N Zhang - Frontiers in Immunology, 2023 - frontiersin.org
Ovarian cancer metastasis occurs primarily in the peritoneal cavity. Orchestration of cancer
cells with various cell types, particularly macrophages, in the peritoneal cavity creates a …