Ageing and rejuvenation of tissue stem cells and their niches
Most adult organs contain regenerative stem cells, often organized in specific niches. Stem
cell function is critical for tissue homeostasis and repair upon injury, and it is dependent on …
cell function is critical for tissue homeostasis and repair upon injury, and it is dependent on …
Immune and inflammatory networks in myocardial infarction: current research and its potential implications for the clinic
A Anzai, S Ko, K Fukuda - International journal of molecular sciences, 2022 - mdpi.com
Despite recent scientific and technological advances, myocardial infarction (MI) still
represents a major global health problem, leading to high morbidity and mortality worldwide …
represents a major global health problem, leading to high morbidity and mortality worldwide …
Monocytes re-enter the bone marrow during fasting and alter the host response to infection
Diet profoundly influences physiology. Whereas over-nutrition elevates risk for disease via
its influence on immunity and metabolism, caloric restriction and fasting appear to be …
its influence on immunity and metabolism, caloric restriction and fasting appear to be …
Clinical Pathway for Coronary Atherosclerosis in Patients Without Conventional Modifiable Risk Factors: JACC State-of-the-Art Review
GA Figtree, ST Vernon, JA Harmer, MP Gray… - Journal of the American …, 2023 - jacc.org
Reducing the incidence and prevalence of standard modifiable cardiovascular risk factors
(SMuRFs) is critical to tackling the global burden of coronary artery disease (CAD) …
(SMuRFs) is critical to tackling the global burden of coronary artery disease (CAD) …
Adherence to the Mediterranean diet: impact of geographical location of the observations
The Mediterranean diet has emerged as a comprehensive lifestyle, including specific foods
and meal composition and a set of behavioural and social features. Adherence to the …
and meal composition and a set of behavioural and social features. Adherence to the …
Clonal hematopoiesis, cardiovascular events and treatment benefit in 63,700 individuals from five TIMI randomized trials
Clonal hematopoiesis of indeterminate potential (CHIP) has been associated with an
increased risk of cardiovascular (CV) disease in the general population. Currently, it is …
increased risk of cardiovascular (CV) disease in the general population. Currently, it is …
Wearable accelerometer-derived physical activity and incident disease
Physical activity is regarded as favorable to health but effects across the spectrum of human
disease are poorly quantified. In contrast to self-reported measures, wearable …
disease are poorly quantified. In contrast to self-reported measures, wearable …
Genomic aging, clonal hematopoiesis, and cardiovascular disease
P Natarajan - Arteriosclerosis, thrombosis, and vascular biology, 2023 - Am Heart Assoc
Chronologic age is the dominant risk factor for coronary artery disease but the features of
aging promoting coronary artery disease are poorly understood. Advances in human …
aging promoting coronary artery disease are poorly understood. Advances in human …
Bone marrow inflammatory memory in cardiometabolic disease and inflammatory comorbidities
I Mitroulis, G Hajishengallis… - Cardiovascular …, 2023 - academic.oup.com
Abstract Cardiometabolic disorders are chief causes of morbidity and mortality, with chronic
inflammation playing a crucial role in their pathogenesis. The release of differentiated …
inflammation playing a crucial role in their pathogenesis. The release of differentiated …
Long-term longitudinal analysis of 4,187 participants reveals insights into determinants of clonal hematopoiesis
Clonal hematopoiesis of indeterminate potential (CHIP) is linked to diverse aging-related
diseases, including hematologic malignancy and atherosclerotic cardiovascular disease …
diseases, including hematologic malignancy and atherosclerotic cardiovascular disease …