Advances of mesenchymal stem cells and their derived extracellular vesicles as a promising therapy for acute respiratory distress syndrome: from bench to clinic

X Zhuang, Y Jiang, X Yang, L Fu, L Luo… - Frontiers in …, 2023 - frontiersin.org
Acute respiratory distress syndrome (ARDS) is an acute inflammatory lung injury
characterized by diffuse alveolar damage. The period prevalence of ARDS was 10.4% of …

[HTML][HTML] Mesenchymal stem cell-derived exosomes as delivery vehicles for non-coding RNAs in lung diseases

Y Feng, K Guo, J Jiang, S Lin - Biomedicine & Pharmacotherapy, 2024 - Elsevier
The burden of lung diseases is gradually increasing with an increase in the average human
life expectancy. Therefore, it is necessary to identify effective methods to treat lung diseases …

Extracellular vesicles as human therapeutics: A scoping review of the literature

C Fusco, G De Rosa, I Spatocco… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs) are released by all cells and contribute to cell‐to‐cell
communication. The capacity of EVs to target specific cells and to efficiently deliver a …

Proteomic profiling of mesenchymal stem cell‐derived extracellular vesicles: Impact of isolation methods on protein cargo

M Abyadeh, S Mirshahvaladi… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs) are nanosized vesicles with a lipid bilayer that are secreted by
cells and play a critical role in cell‐to‐cell communication. Despite the promising reports …

[PDF][PDF] Mesenchymal stem cells and their derived exosomes for ALI/ARDS: A promising therapy

D Liang, C Liu, M Yang - Heliyon, 2023 - cell.com
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a serious clinical
syndrome with a high morbidity and mortality. Presently, therapeutic approaches for …

Clinical Trials of Mesenchymal Stem Cells for the Treatment of COVID 19

E Zendedel, L Tayebi, M Nikbakht… - Current Stem Cell …, 2024 - ingentaconnect.com
Mesenchymal Stem Cells (MSCs) are being investigated as a treatment for a novel viral
disease owing to their immunomodulatory, anti-inflammatory, tissue repair and regeneration …

Manufacturing, quality control, and GLP-grade preclinical study of nebulized allogenic adipose mesenchymal stromal cells-derived extracellular vesicles

J Wang, Z Chen, Z Zhang, M Shen, B Zhao… - Stem Cell Research & …, 2024 - Springer
Background Human adipose stromal cells-derived extracellular vesicles (haMSC-EVs) have
been shown to alleviate inflammation in acute lung injury (ALI) animal models. However …

Application potential of extracellular vesicles derived from mesenchymal stem cells in renal diseases

E Li, J Xu, N Liu, Q Xiong, W Zhang, Y Gong… - Stem Cells, 2024 - academic.oup.com
The high prevalence and complex etiology of renal diseases already impose a heavy
disease burden on patients and society. In certain kidney diseases such as acute kidney …

The Role of Extracellular Vesicles in the Pathogenesis and Treatment of Rheumatoid Arthritis and Osteoarthritis

E Bakinowska, K Kiełbowski, A Pawlik - Cells, 2023 - mdpi.com
Cells can communicate with each other through extracellular vesicles (EVs), which are
membrane-bound structures that transport proteins, lipids and nucleic acids. These …

Mesenchymal Stem Cells on Mortality in COVID-19 Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

J Qin, G Wang, D Han - Stem Cell Reviews and Reports, 2024 - Springer
Abstract Background The Coronavirus disease-2019 (COVID-19) pandemic continues, and
the death toll continues to surge. This meta-analysis aimed to determine the efficacy of …