Results The results demonstrated that the yields of total DNA extracted using either Maxwell
or Cobas methods were significantly higher compared to the QIAamp method (p< 0.001) …

Archived formalin-fixed, paraffin-embedded (FFPE) tissue samples are being increasingly
used in molecular cancer research. Compared with fresh-frozen tissue, the nucleic acid …

The aim of this study is to investigate the effects of formalin fixation on the degradation of
DNA molecules in five different healthy tissues exempted during the autopsy, as well as the …

Purpose Breast cancer has a high prevalence in Korea. To achieve personalized therapy for
breast cancer, long-term follow-up specimens are needed for next-generation sequencing …

Background: Formalin-fixed paraffin-embedded (FFPE) tissue blocks are routinely preserved
after pathological diagnosis and possess tremendous potential for biomarker discovery …

Sporotrichosis is a chronic, cosmopolitan granulomatous mycosis that affects humans and
animals. The infection is caused by the dimorphic fungi Sporothrix sp. The aims of the …

The standardized preanalytical code (SPREC) aggregates warm ischemia (WIT), cold
ischemia (CIT), and fixation times (FIT) in a precise format. Despite its growing importance …

Background FFPE tissue samples are commonly used in biomedical research and are a
valuable source for next-generation sequencing in oncology, however, extracting RNA from …

We report on the use of a DNA staining dye to locate and record nucleated osteocytes and
other bone-related cells within sections of archived formalin-fixed and paraffin-embedded …

Abstract Most Departments of Pathology around the world have a considerable archive of
formalin-fixed paraffin-embedded (FFPE) tissue suitable for molecular assessment. This …