Bridging thrombolysis achieved better outcomes than direct thrombectomy after large vessel occlusion: an updated meta-analysis

Y Wang, X Wu, C Zhu, M Mossa-Basha, A Malhotra - Stroke, 2021 - Am Heart Assoc
The utility and necessity of pretreatment with intravenous thrombolysis (IVT) before
mechanical thrombectomy (MT) remains an issue of strong debate. This study aims to …

The multifaceted role of astrocyte connexin 43 in ischemic stroke through forming hemichannels and gap junctions

Z Liang, X Wang, Y Hao, L Qiu, Y Lou, Y Zhang… - Frontiers in …, 2020 - frontiersin.org
Ischemic stroke is a multi-factorial cerebrovascular disease with high worldwide morbidity
and mortality. In the past few years, multiple studies have revealed the underlying …

Stress hyperglycemia in patients with acute ischemic stroke due to large vessel occlusion undergoing mechanical thrombectomy

G Merlino, S Pez, GL Gigli, M Sponza… - Frontiers in …, 2021 - frontiersin.org
Stress hyperglycemia may impair outcomes in patients with acute ischemic stroke (AIS)
undergoing mechanical thrombectomy (MT). The glucose-to-glycated hemoglobin ratio …

Intravenous thrombolysis before mechanical thrombectomy for acute ischemic stroke: a meta‐analysis

H Du, H Lei, G Ambler, S Fang, R He… - Journal of the …, 2021 - Am Heart Assoc
Background Whether intravenous thrombolysis before mechanical thrombectomy provides
additional benefit for functional outcome in acute ischemic stroke remains uncertain. We …

Hyperdense middle cerebral artery sign predicts favorable outcome in patients undergoing mechanical thrombectomy

G Merlino, Y Tereshko, S Pez, D Bagatto… - Journal of thrombosis …, 2023 - Springer
Non-contrast computer tomography detects the presence of hyperdense middle cerebral
artery sign (HMCAS). Studies on the prognostic value of HMCAS among patients …

Direct endovascular treatment versus bridging therapy in patients with acute ischemic stroke eligible for intravenous thrombolysis: systematic review and meta …

J Zhang, S Chen, S Shi, Y Zhang, D Kong… - Journal of …, 2022 - jnis.bmj.com
Objective In this review and meta-analysis we sought to compare the efficacy and safety of
direct endovascular thrombectomy (EVT) and bridging therapy for intravenous thrombolysis …

Intravenous thrombolysis before mechanical thrombectomy for acute ischemic stroke due to large vessel occlusion; should we cross that bridge? A systematic review …

HS Ghaith, M Elfil, MD Gabra, AA Nawar… - Neurological …, 2022 - Springer
Background The use of intravenous thrombolysis (IVT) before mechanical thrombectomy
(MT) for acute ischemic stroke due to large vessel occlusion (AIS-LVO) is a debatable …

Mechanical thrombectomy combined with intravenous thrombolysis for acute ischemic stroke: a systematic review and meta-analyses

M Zheng, L Li, L Chen, B Li, C Feng - Scientific Reports, 2023 - nature.com
To assess the clinical value of mechanical thrombectomy (MT) combined with intravenous
thrombolysis (IVT) in acute ischemic stroke (AIS) by comparing it with the MT alone. In this …

Clinical and neuroimaging outcomes of direct thrombectomy vs bridging therapy in large vessel occlusion: analysis of the SELECT cohort study

A Sarraj, J Grotta, GW Albers, AE Hassan, S Blackburn… - Neurology, 2021 - AAN Enterprises
Objective To evaluate the comparative safety and efficacy of direct endovascular
thrombectomy (dEVT) compared to bridging therapy (BT; IV tissue plasminogen activator+ …

Comparative efficacy and safety of bridging strategies with direct mechanical thrombectomy in large vessel occlusion: a systematic review and meta-analysis

X Pan, G Liu, B Wu, X Liu, Y Fang - Medicine, 2019 - journals.lww.com
Background: Whether bridging strategies [intravenous thrombolysis (IVT)+ mechanical
thrombectomy (MT)] are superior to mechanical thrombectomy alone for large vessel …