[HTML][HTML] The role of the immunosuppressive PD-1/PD-L1 checkpoint pathway in the aging process and age-related diseases

A Salminen - Journal of Molecular Medicine, 2024 - Springer
The accumulation of senescent cells within tissues is a hallmark of the aging process.
Senescent cells are also commonly present in many age-related diseases and in the cancer …

[HTML][HTML] Taming neuroinflammation in Alzheimer's disease: The protective role of phytochemicals through the gut− brain axis

Y Kim, J Lim, J Oh - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Alzheimer's disease (AD) is a progressive degenerative neurological condition
characterized by cognitive decline, primarily affecting memory and logical thinking, attributed …

Alliums as Potential Antioxidants and Anticancer Agents

K Iwar, K Ochar, YA Seo, BK Ha, SH Kim - International Journal of …, 2024 - mdpi.com
The genus Allium plants, including onions, garlic, leeks, chives, and shallots, have long
been recognized for their potential health benefits, particularly in oxidative and cancer …

[HTML][HTML] Cinnamic Acid, Perillic Acid, and Tryptophan Metabolites Differentially Regulate Ion Transport and Serotonin Metabolism and Signaling in the Mouse Ileum In …

L Jiang, Y Hao, Q Li, Z Dai - International Journal of Molecular Sciences, 2024 - mdpi.com
Phytochemicals and tryptophan (Trp) metabolites have been found to modulate gut function
and health. However, whether these metabolites modulate gut ion transport and serotonin (5 …

[HTML][HTML] Echinacea purpurea root extract mitigates hepatotoxicity, genotoxicity, and ultrastructural changes induced by hexavalent chromium via oxidative stress …

FM El-Demerdash, MM Karhib, NF Ghanem… - … Science and Pollution …, 2024 - Springer
Environmental and occupational exposure to hexavalent chromium (CrVI) is mostly
renowned as a possible hepatotoxic in mammals. Echinacea purpurea (L.) Moench, a …

[HTML][HTML] A standardized combination of Terminalia chebula and Withania somnifera extracts enhances immune function in adults: a pilot randomized, double-blind …

DP Sadhupati, R Lakshmisudha… - Food & Nutrition …, 2024 - ncbi.nlm.nih.gov
Background The use of botanical medicine has been demonstrated as a potential strategy to
manage or treat a variety of health issues. Terminalia chebula (Retz) fruit and Withania …

Evaluation of Berberis vulgaris Phytochemicals for Targeting PIM1 Kinase in Prostate Cancer: An In silico Approach

M Alam, K Abbas, MT Raza, H Yahya… - … Research Journal of …, 2024 - publish7promo.com
Background: PIM1 kinase is a serine/threonine kinase known for its excessive production in
various human cancers, particularly prostate cancer. This enzyme promotes prostate cancer …

[HTML][HTML] Harnessing the immunomodulatory potential of natural products in precision medicine—a comprehensive review

MG Pillai, H Antony - Exploration of Drug Science, 2024 - explorationpub.com
Traditional medicine systems worldwide utilize natural products (NPs), including plant-
derived compounds, minerals, and organisms, harnessing their healing potential. NPs offer …