Forks in the road for CAR T and CAR NK cell cancer therapies

OK Dagher, AD Posey Jr - Nature Immunology, 2023 - nature.com
The advent of chimeric antigen receptor (CAR) T cell therapy has resulted in unprecedented
long-term clearance of relapse/refractory hematological malignancies in both pediatric and …

In vivo applications of micro/nanorobots

CM Oral, M Pumera - Nanoscale, 2023 - pubs.rsc.org
Untethered robots in the size range of micro/nano-scale offer unprecedented access to hard-
to-reach areas of the body. In these challenging environments, autonomous task completion …

A Novel Superparamagnetic Multifunctional Nerve Scaffold: A Remote Actuation Strategy to Boost In Situ Extracellular Vesicles Production for Enhanced Peripheral …

B Xia, X Gao, J Qian, S Li, B Yu, Y Hao… - Advanced …, 2024 - Wiley Online Library
Extracellular vesicles (EVs) have inherent advantages over cell‐based therapies in
regenerative medicine because of their cargos of abundant bioactive cues. Several …

Development and application of nanomaterials, nanotechnology and nanomedicine for treating hematological malignancies

J Li, Q Wang, Y Han, L Jiang, S Lu, B Wang… - Journal of Hematology & …, 2023 - Springer
Hematologic malignancies (HMs) pose a serious threat to patients' health and life, and the
five-year overall survival of HMs remains low. The lack of understanding of the pathogenesis …

A Soft Biodegradable Chitosan‐Based Medical Microrobot with Optimized Structural Design and X‐Ray Visibility for Targeted Vessel Chemoembolization

G Go, HW Song, M Nan, J Lee, S Kim… - Advanced Functional …, 2023 - Wiley Online Library
Although many medical microrobots have been developed for treating diseases, their
designs have not been optimized for disease environments and their functionality and …

A magnetically controlled guidewire robot system with steering and propulsion capabilities for vascular interventional surgery

S Fu, B Chen, D Li, J Han, S Xu, S Wang… - Advanced Intelligent …, 2023 - Wiley Online Library
Magnetically manipulated interventional robotic systems offer outstanding advantages for
improving vascular interventions, including minimizing radiation exposure to physicians and …

Living Cell‐Derived Intelligent Nanobots for Precision Oncotherapy

L Zhou, K Li, Y Liu, R Zhang, Y Yao… - Advanced Functional …, 2024 - Wiley Online Library
The progress of precision oncology medicine is always limited by the tumor off‐targeting, the
drug side effects, and the treatment inefficiency due to the complex and ever‐changing …

Biohybrid magnetic microrobots: An intriguing and promising platform in biomedicine

S Zhu, Y Cheng, J Wang, G Liu, T Luo, X Li, S Yang… - Acta Biomaterialia, 2023 - Elsevier
Biohybrid magnetic microrobots (BMMs) have emerged as an exciting class of microrobots
and have been considered as a promising platform in biomedicine. Many microorganisms …

Cell-based intelligent micro/nanorobots for precise regulation and active biotherapy

G Huang, T Yin, B Zhang, A Ma, T Kang, Y He, Y Long… - Matter, 2023 - cell.com
Precision medicine has shown great promise in the field of individual biomedicine and its
clinical application. However, accurate and efficient treatment remains challenging due to …

Roadmap for Clinical Translation of Mobile Microrobotics

U Bozuyuk, P Wrede, E Yildiz, M Sitti - Advanced Materials, 2024 - Wiley Online Library
Medical microrobotics is an emerging field to revolutionize clinical applications in
diagnostics and therapeutics of various diseases. On the other hand, the mobile …