Influence of follicular fluid and cumulus cells on oocyte quality: clinical implications

MG Da Broi, VSI Giorgi, F Wang, DL Keefe… - Journal of assisted …, 2018 - Springer
An equilibrium needs to be established by the cellular and acellular components of the
ovarian follicle if developmental competence is to be acquired by the oocyte. Both cumulus …

[HTML][HTML] Cyclooxygenase-2 in endometriosis

ZZ Lai, HL Yang, SY Ha, KK Chang, J Mei… - … journal of biological …, 2019 - ncbi.nlm.nih.gov
Endometriosis (EMS) is the most common gynecological disease in women of reproductive
age, and it is associated with chronic pelvic pain, dyspareunia and infertility. As a …

Endometriosis and polycystic ovary syndrome are diametric disorders

NL Dinsdale, BJ Crespi - Evolutionary applications, 2021 - Wiley Online Library
Evolutionary and comparative approaches can yield novel insights into human adaptation
and disease. Endometriosis and polycystic ovary syndrome (PCOS) each affect up to 10% of …

The role of oxidative stress and membrane transport systems during endometriosis: a fresh look at a busy corner

SG Vitale, S Capriglione, I Peterlunger… - Oxidative medicine …, 2018 - Wiley Online Library
Endometriosis is a condition characterized by the presence of endometrial tissue outside the
uterine cavity, leading to a chronic inflammatory reaction. It is one of the most widespread …

Oxidative stress and oocyte quality: ethiopathogenic mechanisms of minimal/mild endometriosis-related infertility

MG Da Broi, PA Navarro - Cell and Tissue Research, 2016 - Springer
Endometriosis, a highly prevalent gynecological disease, is often associated with infertility,
even in its milder forms (minimal and mild endometriosis). However, no consensus has been …

[HTML][HTML] Defining the genetic profile of endometriosis

L Vassilopoulou, M Matalliotakis… - Experimental and …, 2019 - spandidos-publications.com
Endometriosis is a pathological condition which has been extensively studied, since its
pathophysiology stems from a broad spectrum of environmental influences and genetic …

Transcriptomic analysis of cumulus cells shows altered pathways in patients with minimal and mild endometriosis

CM Da Luz, MG Da Broi, LO Koopman, JR Plaça… - Scientific Reports, 2022 - nature.com
Endometriosis is a chronic inflammatory disorder that is highly associated with infertility. This
association seems to be related to oocyte impairment, mainly in the initial stages of …

Epigenetic alterations of CYP19A1 gene in Cumulus cells and its relevance to infertility in endometriosis

E Hosseini, F Mehraein, M Shahhoseini… - Journal of assisted …, 2016 - Springer
Purpose The purpose of the present study was to investigate the epigenetic mechanisms
responsible for the aberrant aromatase expression (CYP19A1) in Cumulus Cells (CCs) of …

[HTML][HTML] Endometriosis and in vitro fertilisation

L Vassilopoulou, M Matalliotakis… - Experimental and …, 2018 - spandidos-publications.com
The aim of the present review was to discuss a matter of concern in the clinical field of
obstetrics/gynecology, namely the potency of in vitro fertilization (IVF) in the management of …

Granulosa cell biomarkers to predict pregnancy in ART: pieces to solve the puzzle

RJ Kordus, HA LaVoie - Reproduction, 2017 - rep.bioscientifica.com
Cumulus and mural granulosa cells of the ovarian follicle surround and interact with the
developing oocyte. These follicular cells reflect the oocyte's overall health and may indicate …