Brillouin microscopy: an emerging tool for mechanobiology

R Prevedel, A Diz-Muñoz, G Ruocco, G Antonacci - Nature methods, 2019 - nature.com
The role and importance of mechanical properties of cells and tissues in cellular function,
development and disease has widely been acknowledged, however standard techniques …

Recent progress and current opinions in Brillouin microscopy for life science applications

G Antonacci, T Beck, A Bilenca, J Czarske… - Biophysical …, 2020 - Springer
Many important biological functions and processes are reflected in cell and tissue
mechanical properties such as elasticity and viscosity. However, current techniques used for …

Brillouin light scattering: applications in biomedical sciences

F Palombo, D Fioretto - Chemical reviews, 2019 - ACS Publications
Brillouin spectroscopy and imaging are emerging techniques in analytical science,
biophotonics, and biomedicine. They are based on Brillouin light scattering from acoustic …

Mapping mechanical properties of biological materials via an add-on Brillouin module to confocal microscopes

J Zhang, G Scarcelli - Nature protocols, 2021 - nature.com
Several techniques have been developed over the past few decades to assess the
mechanical properties of biological samples, which has fueled a rapid growth in the fields of …

High-frequency mechanical properties of tumors measured by Brillouin light scattering

J Margueritat, A Virgone-Carlotta, S Monnier… - Physical review …, 2019 - APS
The structure of tumors can be recapitulated as an elastic frame formed by the connected
cytoskeletons of the cells invaded by interstitial and intracellular fluids. The low-frequency …

Biomechanics of subcellular structures by non-invasive Brillouin microscopy

G Antonacci, S Braakman - Scientific Reports, 2016 - nature.com
Cellular biomechanics play a pivotal role in the pathophysiology of several diseases.
Unfortunately, current methods to measure biomechanical properties are invasive and …

Seeing cells in a new light: a renaissance of Brillouin spectroscopy

Z Meng, AJ Traverso, CW Ballmann… - Advances in Optics …, 2016 - opg.optica.org
Over the years, light scattering from acoustic waves has grown to be increasingly important
in the fields of biology and medicine. This type of scattering, known as Brillouin scattering …

Dual Raman-Brillouin microscope for chemical and mechanical characterization and imaging

AJ Traverso, JV Thompson, ZA Steelman… - Analytical …, 2015 - ACS Publications
We present a unique confocal microscope capable of measuring the Raman and Brillouin
spectra simultaneously from a single spatial location. Raman and Brillouin scattering offer …

Stimulated Brillouin scattering microscopic imaging

CW Ballmann, JV Thompson, AJ Traverso, Z Meng… - Scientific reports, 2015 - nature.com
Two-dimensional stimulated Brillouin scattering microscopy is demonstrated for the first time
using low power continuous-wave lasers tunable around 780 nm. Spontaneous Brillouin …

Viscoelasticity of amyloid plaques in transgenic mouse brain studied by Brillouin microspectroscopy and correlative Raman analysis

S Mattana, S Caponi, F Tamagnini… - Journal of innovative …, 2017 - World Scientific
Amyloidopathy is one of the most prominent hallmarks of Alzheimer's disease (AD), the
leading cause of dementia worldwide, and is characterized by the accumulation of amyloid …