Advances in copper complexes as anticancer agents

C Santini, M Pellei, V Gandin, M Porchia… - Chemical …, 2014 - ACS Publications
Medicinal inorganic chemistry offers additional opportunities for the design of therapeutic
agents not accessible to organic compounds. 1− 3 The wide range of coordination numbers …

First-row transition metal compounds containing benzimidazole ligands: An overview of their anticancer and antitumor activity

D Hernández-Romero, S Rosete-Luna… - Coordination Chemistry …, 2021 - Elsevier
Cancer can be defined as an irregular functioning of the cell cycle that results in a
progressive loss of cell differentiation and uncontrolled cell growth. Moreover, despite …

[HTML][HTML] Benzimidazole: A Versatile Scaffold for Drug Discovery and Beyond-A Comprehensive Review of Synthetic Approaches and Recent Advancements in …

ND Mahurkar, ND Gawhale, MN Lokhande, SJ Uke… - Results in …, 2023 - Elsevier
Heterocyclic compounds are foundational in drug discovery, constituting the core structure of
approximately 80% of pharmaceuticals. Benzimidazole, in particular, emerges as a critical …

Cytotoxic copper (II), cobalt (II), zinc (II), and nickel (II) coordination compounds of clotrimazole

S Betanzos-Lara, C Gómez-Ruiz… - Journal of inorganic …, 2012 - Elsevier
Sixteen novel mononuclear CuII, CoII, ZnII, and NiII complexes of the biologically active
ligand clotrimazole (clotri) of the forms [M (clotri) 2Cl2]· nH2O (1–4),[M (clotri) 2Br2]· nH2O (5 …

Synthesis and evaluation of anticancer properties of novel benzimidazole ligand and their cobalt (II) and zinc (II) complexes against cancer cell lines A-2780 and DU …

Ü Yılmaz, S Tekin, N Buğday, K Yavuz… - Inorganica Chimica …, 2019 - Elsevier
Eighteen new cobalt (II) or zinc (II) complexes of benzimidazole bearing 1-benzyl and 2-
phenyl moieties were synthesized from the reaction of appropriate benzimidazole ligands …

2, 6-Bis (2, 6-diethylphenyliminomethyl) pyridine coordination compounds with cobalt (II), nickel (II), copper (II), and zinc (II): synthesis, spectroscopic characterization …

P Martinez-Bulit, A Garza-Ortíz, E Mijangos… - Journal of Inorganic …, 2015 - Elsevier
Coordination compounds with cobalt (II), nickel (II), copper (II) and zinc (II) and the ligand 2,
6-bis (2, 6-diethylphenyliminomethyl) pyridine (L) were synthesized and fully characterized …

Synthesis, Structure, and Antimicrobial Properties of New Cobalt (II) Complexes with 1-Propargylimidazoles

IV Sterkhova, LN Parshina… - Current Organic …, 2024 - ingentaconnect.com
Complexes of cobalt (II) chloride with 1-propargylimidazole, 1-propargyl-2-methylimidazole,
and 1-propargylbenzimidazole ligands were synthesized and studied by FTIR spectroscopy …

Halo-bridged Cu (II) complexes with pyridine–pyrazole ligands: Influence of halogen and ligand lipophilicity on antimicrobial activity

VJ Tamilpriyai, P Nagarasu, KS Dharshini… - Journal of Molecular …, 2023 - Elsevier
A series of five coordinated, doubly halo bridged Cu (II) complexes [Cu 2 (μ-X) 2 (Ln) 2×
2](X= Cl and Br; n= 1, 2 and 3), CuL1Cl, CuL1Br, CuL2Cl, CuL2Br, CuL3Cl and CuL3Br …

Redox-active and DNA-binding coordination complexes of clotrimazole

S Betanzos-Lara, NP Chmel, MT Zimmerman… - Dalton …, 2015 - pubs.rsc.org
DNA interactions of anticancer mononuclear Cu2+, Co2+, Zn2+, and Ni2+ complexes with
the biologically active ligand clotrimazole (clotri) are reported. To fully characterize DNA …

Understanding the Coordination Modes of [Cu(acac)2(imidazole)n=1,2] Adducts by EPR, ENDOR, HYSCORE, and DFT Analysis

N Ritterskamp, K Sharples, E Richards, A Folli… - Inorganic …, 2017 - ACS Publications
The interaction of imidazole with a [Cu (acac) 2] complex was studied using electron
paramagnetic resonance (EPR), electron nuclear double resonance (ENDOR), hyperfine …