An updated overview on the role of small molecules and natural compounds in the “young science” of rejuvenation
G Ribaudo, A Gianoncelli - Antioxidants, 2023 - mdpi.com
Aging is a gradual process that occurs over time which leads to a progressive decline of
cells and tissues. Telomere shortening, genetic instability, epigenetic alteration, and the …
cells and tissues. Telomere shortening, genetic instability, epigenetic alteration, and the …
A possible role for G-quadruplexes formation and DNA methylation at IMOOD gene promoter in Obsessive Compulsive Disorder
Abstract Obsessive Compulsive Disorder (OCD) is a mental health condition still classified
and diagnosed with subjective interview-based assessments and which molecular clues …
and diagnosed with subjective interview-based assessments and which molecular clues …
Crosstalk between G-Quadruplexes and Dnmt3a-Mediated Methylation of the c-MYC Oncogene Promoter
AV Sergeev, AG Loiko, AI Genatullina… - International Journal of …, 2023 - mdpi.com
The methylation of cytosines at CpG sites in DNA, carried out de novo by DNA
methyltransferase Dnmt3a, is a basic epigenetic modification involved in gene regulation …
methyltransferase Dnmt3a, is a basic epigenetic modification involved in gene regulation …
G‐Quadruplexes as Key Transcriptional Regulators in Neglected Trypanosomatid Parasites
L Monti, M Di Antonio - ChemBioChem, 2023 - Wiley Online Library
Abstract G‐quadruplexes (G4s) are nucleic acid secondary structures that have been linked
to the functional regulation of eukaryotic organisms. G4s have been extensively …
to the functional regulation of eukaryotic organisms. G4s have been extensively …
Toward a Better Understanding of G4 Evolution in the 3 Living Kingdoms
A Vannutelli, A Ouangraoua… - Evolutionary …, 2023 - journals.sagepub.com
Background: G-quadruplexes (G4s) are secondary structures in DNA and RNA that impact
various cellular processes, such as transcription, splicing, and translation. Due to their …
various cellular processes, such as transcription, splicing, and translation. Due to their …
Low-Dose Interferon I and III-Based Nasal Sprays: A Good-Looking COVID-19 Vaccine Candidate and a Therapy of the Future?
TN Carp, M Metoudi, B Brown, V Ojha - 2023 - preprints.org
The SARS–CoV-2 infection has caused both acute and chronic COVID–19 disease during
the recent pandemic with emerging more transmissible SARS–CoV–2 Omicron variants …
the recent pandemic with emerging more transmissible SARS–CoV–2 Omicron variants …
G-quadruplex formation in GCK and TM6SF2 are targets for differential DNA methylation in metabolic dysfunction-associated fatty liver disease and type II diabetes …
A Lahnsteiner, V Ellmer, A Oberlercher, Z Lutkeviciute… - bioRxiv, 2024 - biorxiv.org
Background. The alarming increase in global rates of metabolic diseases (MetDs) and their
association with an increased cancer risk renders them a considerable burden on our …
association with an increased cancer risk renders them a considerable burden on our …