The elusive nature of sudden unexpected death in epilepsy (SUDEP) has led to
investigations of mechanisms and identification of biomarkers of this fatal scenario that …

Introduction: Sudden unexpected death in epilepsy (SUDEP) affects about 1 in 1000 people
with epilepsy, and even more in medically refractory epilepsy. As most people are between …

Objective To characterize peri-ictal apnea and postictal asystole in generalized convulsive
seizures (GCS) of intractable epilepsy. Methods This was a prospective, multicenter epilepsy …

Introduction: Peri-ictal breathing dysfunction was proposed as a potential mechanism for
SUDEP. We examined the incidence and risk factors for both ictal (ICA) and post-convulsive …

Objective The processes underlying sudden unexpected death in epilepsy (SUDEP) remain
elusive, but centrally mediated cardiovascular or respiratory collapse is suspected. Volume …

Autonomic dysfunction is implicated from clinical, neuroimaging and experimental studies in
sudden and unexpected death in epilepsy (SUDEP). Neuropathological analysis in SUDEP …

Objective Ictal (ICA) and postconvulsive central apnea (PCCA) have been implicated in
sudden unexpected death in epilepsy (SUDEP) pathomechanisms. Previous studies …

Objective Sudden unexpected death in epilepsy (SUDEP) may arise as a result of
autonomic dysfunction during a seizure. The central autonomic networks (CANs) modulate …

The circumstances surrounding SUDEP suggest autonomic or respiratory collapse, implying
central failure of regulation or recovery. Characterisation of the communication among brain …

Objectives Dysfunctional connectivity and preexisting structural abnormalities of central
autonomic network (CAN) regions have been shown on magnetic resonance imaging (MRI) …