Advances in the Theranostics of Oesophageal Squamous Carcinoma

M Cheng, Q Xin, S Ma, M Ge, F Wang… - Advanced …, 2023 - Wiley Online Library
Oesophageal squamous carcinoma (ESCC) is one of the most lethal human malignancies,
and it is a more aggressive form of oesophageal cancer (EC) that comprises over 90% of all …

Roles of YAP/TAZ in ferroptosis

S Magesh, D Cai - Trends in cell biology, 2022 - cell.com
Ferroptosis is a unique iron-dependent form of regulated cell death. Recently, researchers
found that ferroptosis was sensitive to cell density, regulated by Hippo signaling. This article …

Clock-modified mesenchymal stromal cells therapy rescues molecular circadian oscillation and age-related bone loss via miR142-3p/Bmal1/YAP signaling axis

S Cha, J Wang, SM Lee, Z Tan, Q Zhao, D Bai - Cell Death Discovery, 2022 - nature.com
Age-related bone loss and disease strongly affect the quality of life of the elderly population.
Cellular circadian rhythms have been reported to regulate bone aging, and micro RNAs …

[HTML][HTML] MicroRNA-624-mediated ARRDC3/YAP/HIF1α axis enhances esophageal squamous cell carcinoma cell resistance to cisplatin and paclitaxel

J Yan, L Shi, S Lin, Y Li - Bioengineered, 2021 - ncbi.nlm.nih.gov
Development of chemoresistance remains a major challenge in treating patients suffering
from esophageal squamous cell carcinoma (ESCC), despite treatment advances …

[HTML][HTML] Chaetocin exhibits anticancer effects in esophageal squamous cell carcinoma via activation of Hippo pathway

L Li, H Jiang, Y Li, X Xiang, Y Chu, J Tang, K Liu… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Dysfunction of the Hippo pathway is common in esophageal squamous carcinoma (ESCC).
Chaetocin, a small molecular compound isolated from the marine fungus, exhibits potent …

Potential of the nanoplatform and PROTAC interface to achieve targeted protein degradation through the Ubiquitin–Proteasome system

H Xie, C Zhang - European Journal of Medicinal Chemistry, 2024 - Elsevier
In eukaryotic cells, the ubiquitin–proteasome system (UPS) plays a crucial role in selectively
breaking down specific proteins. The ability of the UPS to target proteins effectively and …

LncRNA GATA2-AS1 suppresses esophageal squamous cell carcinoma progression via the mir-940/PTPN12 axis

Y Niu, Y Guo, Y Li, S Shen, J Liang, W Guo… - Experimental Cell …, 2022 - Elsevier
Esophageal squamous cell carcinoma (ESCC) is a common malignant tumor worldwide.
Long noncoding RNAs (lncRNAs) exhibit a regulatory role in the progression of ESCC. Our …

Arsenic impairs stem cell differentiation via the Hippo signaling pathway

MC Perego, BD McMichael, LJ Bain - Toxicology Research, 2023 - academic.oup.com
Arsenic is a ubiquitous toxic metalloid, with over 150 million people exposed to arsenic
concentrations above the current 10 ppb drinking water standard through contaminated food …

亚砷酸钠对AML12 肝细胞氧化应激, 凋亡损伤及Hippo 信号通路的影响

赵哲仪, 王正蓉, 方兴艳, 王甜, 谢婷婷 - 中国组织工程研究, 2022 - cjter.com
亚砷酸钠对AML12 肝细胞氧化应激,凋亡损伤及Hippo 信号通路的影响 Page 1 4186|中国组织
工程研究|第26卷|第26期|2022年9月 中国组织工程研究 Chinese Journal of Tissue Engineering …

Association between circ_0004365 and cisplatin resistance in esophageal squamous cell carcinoma

M Yamada, K Tanaka, K Yamamoto… - Oncology …, 2023 - spandidos-publications.com
Cisplatin is one of the most predominant drugs for the chemotherapy of esophageal
squamous cell carcinoma (ESCC); however, the underlying resistance mechanisms are still …