Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected millions
worldwide with a high mortality rate due to a lack of definitive treatment. Despite having a …

Connective tissue disease (CTD) related interstitial lung disease (CTD-ILD) is one of the
leading causes of morbidity and mortality of CTD. Clinically, CTD-ILD is highly heterogenous …

Galectin (Gal)-3 is a profibrotic β-galactoside-binding lectin that plays a key role in the
pathogenesis of idiopathic pulmonary fibrosis (IPF) and IPF exacerbations. TD139 is a novel …

Objective Interstitial lung disease (ILD) in systemic sclerosis (SS c) runs a highly variable
course, and prediction tools are highly desired. The aim of this study was to assess the …

Biomarkers have the potential to become central to the clinical evaluation and monitoring of
patients with chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype …

Idiopathic pulmonary fibrosis (IPF), the most lethal form of interstitial pneumonia of unknown
cause, is associated with a specific radiological and histopathological pattern (the so-called …

Idiopathic pulmonary fibrosis (IPF) is a debilitating condition where excess collagen
deposition occurs in the extracellular matrix. At first sight, it is expected that the level of …

Idiopathic pulmonary fibrosis (IPF) is a chronic, debilitating, fibrotic lung disease leading to
respiratory failure and ultimately to death. Being the prototype of interstitial lung diseases …

Abstract Background Matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs
(TIMPs) play important roles in the turnover of extracellular matrix and in the pathogenesis of …

The heterogeneity of idiopathic pulmonary fibrosis (IPF) limits its diagnosis and treatment.
The association between the pathophysiological features and the serum protein signatures …