mRNA in the context of protein replacement therapy

T Vavilis, E Stamoula, A Ainatzoglou, A Sachinidis… - Pharmaceutics, 2023 - mdpi.com
Protein replacement therapy is an umbrella term used for medical treatments that aim to
substitute or replenish specific protein deficiencies that result either from the protein being …

[HTML][HTML] The inorganic pyrophosphatases of microorganisms: a structural and functional review

R García-Contreras, J de la Mora, HM Mora-Montes… - PeerJ, 2024 - peerj.com
Pyrophosphatases (PPases) are enzymes that catalyze the hydrolysis of pyrophosphate
(PPi), a byproduct of the synthesis and degradation of diverse biomolecules. The …

Development of a paper-based transcription aptasensor for convenient urinary uric acid self-testing

C Zhang, W Dang, J Zhang, C Wang, P Zhong… - International Journal of …, 2024 - Elsevier
The abnormal uric acid (UA) level in urine can serve as warning signals of many diseases,
such as gout and metabolic cardiovascular diseases. The current methods for detecting UA …

Thermophilic Inorganic Pyrophosphatase Ton1914 from Thermococcus onnurineus NA1 Removes the Inhibitory Effect of Pyrophosphate

Y Li, X Yang, R Gao - International Journal of Molecular Sciences, 2022 - mdpi.com
Pyrophosphate (PPi) is a byproduct of over 120 biosynthetic reactions, and an
overabundance of PPi can inhibit industrial synthesis. Pyrophosphatases (PPases) can …

Stochastic Molecular Reaction Queueing Network Modeling for in Vitro Transcription Process

K Wang, W Xie, H Zheng - 2023 Winter Simulation Conference …, 2023 - ieeexplore.ieee.org
To facilitate a rapid response to pandemic threats, this paper focuses on developing a
mechanistic simulation model for in vitro transcription (IVT) process, a crucial step in mRNA …

[PDF][PDF] mRNA in the context of protein replacement therapy. Pharmaceutics 2023; 15: 166

T Vavilis, E Stamoula, A Ainatzoglou, A Sachinidis… - 2023 - ikee.lib.auth.gr
Protein replacement therapy is an umbrella term used for medical treatments that aim to
substitute or replenish specific protein deficiencies that result either from the protein being …