Neuronal growth cones navigate over long distances along specific pathways to find their
correct targets. The mechanisms and molecules that direct this pathfinding are the topics of …

▪ Abstract Growth cones, the hand-like structures at the tip of growing neurites, possess
remarkable abilities to detect directional cues. On their way to their targets they traverse a …

Neurofascin, NrCAM, L1, and NgCAM are a family of Ig/FNIII cell adhesion molecules that
share ankyrin-binding activity in their cytoplasmic domains, and are candidates to form …

Autism spectrum disorders (ASDs) are a complex neurodevelopmental disorder that display
a triad of core behavioral deficits including restricted interests, often accompanied by …

Saltatory conduction requires high-density accumulation of Na+ channels at the nodes of
Ranvier. Nodal Na+ channel clustering in the peripheral nervous system is regulated by …

In glutamatergic synapses, glutamate receptors (GluRs) associate with many other proteins
involved in scaffolding and signal transduction. The ontogeny of these postsynaptic density …

Ranvier nodes are flanked by paranodal regions, at the level of which oligodendrocytes or
Schwann cells interact closely with axons. Paranodes play a critical role in the physiological …

Cell–cell interactions play important roles during metazoan development, especially in
nervous system formation. A number of different gene families that convey specific adhesive …

Bipolar, amacrine, and retinal ganglion cells elaborate arbors and form synapses within the
inner plexiform layer (IPL) of the vertebrate retina. Specific subsets of these neuronal types …

Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that
are expressed exclusively in the nervous system. The subgroup consists of six members …