Artificial intelligence-assisted selection and efficacy prediction of antineoplastic strategies for precision cancer therapy
ZHE Zhang, X Wei - Seminars in Cancer Biology, 2023 - Elsevier
The rapid development of artificial intelligence (AI) technologies in the context of the vast
amount of collectable data obtained from high-throughput sequencing has led to an …
amount of collectable data obtained from high-throughput sequencing has led to an …
High-throughput genomics and clinical outcome in hard-to-treat advanced cancers: results of the MOSCATO 01 trial
High-throughput genomic analyses may improve outcomes in patients with advanced
cancers. MOSCATO 01 is a prospective clinical trial evaluating the clinical benefit of this …
cancers. MOSCATO 01 is a prospective clinical trial evaluating the clinical benefit of this …
Added value of whole-exome and transcriptome sequencing for clinical molecular screenings of advanced cancer patients with solid tumors
F Koeppel, A Bobard, C Lefebvre, M Pedrero… - The Cancer …, 2018 - journals.lww.com
Comprehensive genomic profiling using high-throughput sequencing brings a wealth of
information, and its place in the clinical setting has been increasingly prominent. This review …
information, and its place in the clinical setting has been increasingly prominent. This review …
[HTML][HTML] Relevance of a molecular tumour board (MTB) for patients' enrolment in clinical trials: experience of the Institut Curie
C Basse, C Morel, M Alt, MP Sablin, C Franck… - ESMO open, 2018 - Elsevier
Background High throughput molecular screening techniques allow the identification of
multiple molecular alterations, some of which are actionable and can be targeted by …
multiple molecular alterations, some of which are actionable and can be targeted by …
[HTML][HTML] Impact of molecular tumour board discussion on targeted therapy allocation in advanced prostate cancer
PHJ Slootbeek, ISH Kloots, M Smits… - British Journal of …, 2022 - nature.com
Background Molecular tumour boards (MTB) optimally match oncological therapies to
patients with genetic aberrations. Prostate cancer (PCa) is underrepresented in these MTB …
patients with genetic aberrations. Prostate cancer (PCa) is underrepresented in these MTB …
[HTML][HTML] Does smoking alter the mutation profile of human papillomavirus–driven head and neck cancers?
H Mirghani, L Lacroix, C Rossoni, R Sun… - European Journal of …, 2018 - Elsevier
Background Human papillomavirus (HPV)-driven oropharyngeal cancer (OPC) patients are
characterised by a better prognosis than their HPV-negative counterparts. However, this …
characterised by a better prognosis than their HPV-negative counterparts. However, this …
[HTML][HTML] The cost of molecular-guided therapy in oncology: a prospective cost study alongside the MOSCATO trial
A Pagès, S Foulon, Z Zou, L Lacroix, F Lemare… - Genetics in …, 2017 - Elsevier
Aim There is increasing use of molecular technologies to guide cancer treatments, but few
cost data are available. Our objective was to assess the costs of molecular-guided therapy …
cost data are available. Our objective was to assess the costs of molecular-guided therapy …
Whole exome sequencing in molecular diagnostics of cancer decreases over time: evidence from a cost analysis in the French setting
A Bayle, N Droin, B Besse, Z Zou, Y Boursin… - The European Journal of …, 2021 - Springer
Objectives Although high-throughput sequencing is revolutionising medicine, data on the
actual cost of whole exome sequencing (WES) applications are needed. We aimed at …
actual cost of whole exome sequencing (WES) applications are needed. We aimed at …
Quelle vision des biomarqueurs en 2017? Promesses et défis de la médecine personnalisée en oncologie
Résumé L'utilisation de biomarqueurs en oncologie permet de sélectionner des populations
pouvant bénéficier de traitements anticancéreux plus efficaces et moins toxiques, et …
pouvant bénéficier de traitements anticancéreux plus efficaces et moins toxiques, et …
Impact of a Molecular Sequencing Systematic at Diagnosis in Digestive Oncology: Experience of a French Center
B de Rauglaudre, E Norguet-Monnereau… - Clinical Oncology …, 2021 - inserm.hal.science
Introduction: Tumor-based molecular profiling has increased in the area of precision
medicine. Their routine use is still limited by accessibility, cost and availability of tumor …
medicine. Their routine use is still limited by accessibility, cost and availability of tumor …