Mechanisms of virus assembly
JD Perlmutter, MF Hagan - Annual review of physical chemistry, 2015 - annualreviews.org
Viruses are nanoscale entities containing a nucleic acid genome encased in a protein shell
called a capsid and in some cases are surrounded by a lipid bilayer membrane. This review …
called a capsid and in some cases are surrounded by a lipid bilayer membrane. This review …
Self-assembly and transformation of hybrid nano-objects and nanostructures under equilibrium and non-equilibrium conditions
S Mann - Nature materials, 2009 - nature.com
Understanding how chemically derived processes control the construction and organization
of matter across extended and multiple length scales is of growing interest in many areas of …
of matter across extended and multiple length scales is of growing interest in many areas of …
Supramolecular dendritic liquid quasicrystals
A large number of synthetic and natural compounds self-organize into bulk phases
exhibiting periodicities on the 10-8–10-6 metre scale as a consequence of their molecular …
exhibiting periodicities on the 10-8–10-6 metre scale as a consequence of their molecular …
Virus shapes and buckling transitions in spherical shells
We show that the icosahedral packings of protein capsomeres proposed by Caspar and
Klug for spherical viruses become unstable to faceting for sufficiently large virus size, in …
Klug for spherical viruses become unstable to faceting for sufficiently large virus size, in …
Equilibrium mechanisms of self-limiting assembly
Self-assembly is a ubiquitous process in synthetic and biological systems, broadly defined
as the spontaneous organization of multiple subunits (macromolecules, particles, etc.) into …
as the spontaneous organization of multiple subunits (macromolecules, particles, etc.) into …
Origin of icosahedral symmetry in viruses
With few exceptions, the shells (capsids) of sphere-like viruses have the symmetry of an
icosahedron and are composed of coat proteins (subunits) assembled in special motifs, the …
icosahedron and are composed of coat proteins (subunits) assembled in special motifs, the …
[HTML][HTML] Dynamic pathways for viral capsid assembly
MF Hagan, D Chandler - Biophysical journal, 2006 - cell.com
We develop a class of models with which we simulate the assembly of particles into T1
capsidlike objects using Newtonian dynamics. By simulating assembly for many different …
capsidlike objects using Newtonian dynamics. By simulating assembly for many different …
Modeling viral capsid assembly
MF Hagan - Advances in Chemical Physics: Volume 155, 2014 - Wiley Online Library
Viruses play a role in a significant portion of human diseases, as well as those of other
animals, plants, and bacteria. This chapter focuses on the use of theoretical and …
animals, plants, and bacteria. This chapter focuses on the use of theoretical and …
Core-controlled polymorphism in virus-like particles
This study concerns the self-assembly of virus-like particles (VLPs) composed of an
icosahedral virus protein coat encapsulating a functionalized spherical nanoparticle core …
icosahedral virus protein coat encapsulating a functionalized spherical nanoparticle core …