Mechanisms of virus assembly

JD Perlmutter, MF Hagan - Annual review of physical chemistry, 2015 - annualreviews.org
Viruses are nanoscale entities containing a nucleic acid genome encased in a protein shell
called a capsid and in some cases are surrounded by a lipid bilayer membrane. This review …

Self-assembly and transformation of hybrid nano-objects and nanostructures under equilibrium and non-equilibrium conditions

S Mann - Nature materials, 2009 - nature.com
Understanding how chemically derived processes control the construction and organization
of matter across extended and multiple length scales is of growing interest in many areas of …

Supramolecular dendritic liquid quasicrystals

X Zeng, G Ungar, Y Liu, V Percec, AE Dulcey… - Nature, 2004 - nature.com
A large number of synthetic and natural compounds self-organize into bulk phases
exhibiting periodicities on the 10-8–10-6 metre scale as a consequence of their molecular …

Physical virology

WH Roos, R Bruinsma, GJL Wuite - Nature physics, 2010 - nature.com
Viruses are nanosized, genome-filled protein containers with remarkable thermodynamic
and mechanical properties. They form by spontaneous self-assembly inside the crowded …

Virus shapes and buckling transitions in spherical shells

J Lidmar, L Mirny, DR Nelson - Physical Review E, 2003 - APS
We show that the icosahedral packings of protein capsomeres proposed by Caspar and
Klug for spherical viruses become unstable to faceting for sufficiently large virus size, in …

Equilibrium mechanisms of self-limiting assembly

MF Hagan, GM Grason - Reviews of modern physics, 2021 - APS
Self-assembly is a ubiquitous process in synthetic and biological systems, broadly defined
as the spontaneous organization of multiple subunits (macromolecules, particles, etc.) into …

Origin of icosahedral symmetry in viruses

R Zandi, D Reguera, RF Bruinsma… - Proceedings of the …, 2004 - National Acad Sciences
With few exceptions, the shells (capsids) of sphere-like viruses have the symmetry of an
icosahedron and are composed of coat proteins (subunits) assembled in special motifs, the …

[HTML][HTML] Dynamic pathways for viral capsid assembly

MF Hagan, D Chandler - Biophysical journal, 2006 - cell.com
We develop a class of models with which we simulate the assembly of particles into T1
capsidlike objects using Newtonian dynamics. By simulating assembly for many different …

Modeling viral capsid assembly

MF Hagan - Advances in Chemical Physics: Volume 155, 2014 - Wiley Online Library
Viruses play a role in a significant portion of human diseases, as well as those of other
animals, plants, and bacteria. This chapter focuses on the use of theoretical and …

Core-controlled polymorphism in virus-like particles

J Sun, C DuFort, MC Daniel, A Murali… - Proceedings of the …, 2007 - National Acad Sciences
This study concerns the self-assembly of virus-like particles (VLPs) composed of an
icosahedral virus protein coat encapsulating a functionalized spherical nanoparticle core …