Impaired adipogenesis and dysfunctional adipose tissue in human hypertrophic obesity

A Hammarstedt, S Gogg, S Hedjazifar… - Physiological …, 2018 - journals.physiology.org
The subcutaneous adipose tissue (SAT) is the largest and best storage site for excess lipids.
However, it has a limited ability to expand by recruiting and/or differentiating available …

Intermuscular adipose tissue in metabolic disease

BH Goodpaster, BC Bergman, AM Brennan… - Nature Reviews …, 2023 - nature.com
Intermuscular adipose tissue (IMAT) is a distinct adipose depot described in early reports as
a 'fatty replacement'or 'muscle fat infiltration'that was linked to ageing and neuromuscular …

Adipose‐derived mesenchymal stromal/stem cells: tissue localization, characterization, and heterogeneity

PC Baer, H Geiger - Stem cells international, 2012 - Wiley Online Library
Adipose tissue as a stem cell source is ubiquitously available and has several advantages
compared to other sources. It is easily accessible in large quantities with minimal invasive …

Type-2 pericytes participate in normal and tumoral angiogenesis

A Birbrair, T Zhang, ZM Wang… - … of Physiology-Cell …, 2014 - journals.physiology.org
Tissue growth and function depend on vascularization, and vascular insufficiency or excess
exacerbates many human diseases. Identification of the biological processes involved in …

Adipose tissue stem cells meet preadipocyte commitment: going back to the future [S]

WP Cawthorn, EL Scheller, OA MacDougald - Journal of lipid research, 2012 - ASBMB
White adipose tissue (WAT) is perhaps the most plastic organ in the body, capable of
regeneration following surgical removal and massive expansion or contraction in response …

Role of pericytes in skeletal muscle regeneration and fat accumulation

A Birbrair, T Zhang, ZM Wang, ML Messi… - Stem cells and …, 2013 - liebertpub.com
Stem cells ensure tissue regeneration, while overgrowth of adipogenic cells may
compromise organ recovery and impair function. In myopathies and muscle atrophy …

The tunica adventitia of human arteries and veins as a source of mesenchymal stem cells

M Corselli, CW Chen, B Sun, S Yap… - Stem cells and …, 2012 - liebertpub.com
We previously demonstrated that human pericytes, which encircle capillaries and
microvessels, give rise in culture to genuine mesenchymal stem cells (MSCs). This raised …

Stromal vascular progenitors in adult human adipose tissue

L Zimmerlin, VS Donnenberg, ME Pfeifer… - Cytometry Part A …, 2010 - Wiley Online Library
The in vivo progenitor of culture‐expanded mesenchymal‐like adipose‐derived stem cells
(ADSC) remains elusive, owing in part to the complex organization of stromal cells …

Dual origin of mesenchymal stem cells contributing to organ growth and repair

J Feng, A Mantesso, C De Bari… - Proceedings of the …, 2011 - National Acad Sciences
In many adult tissues, mesenchymal stem cells (MSCs) are closely associated with
perivascular niches and coexpress many markers in common with pericytes. The ability of …

Adipose-derived stem cells as a tool in cell-based therapies

A Bajek, N Gurtowska, J Olkowska… - Archivum Immunologiae …, 2016 - Springer
Recent development in stem cell isolation methods and expansion under laboratory
conditions create an opportunity to use those aforementioned cells in tissue engineering …