Pharmacogenetics guidelines: overview and comparison of the DPWG, CPIC, CPNDS, and RNPGx guidelines

H Abdullah-Koolmees, AM Van Keulen… - Frontiers in …, 2021 - frontiersin.org
Many studies have shown that the efficacy and risk of side effects of drug treatment is
influenced by genetic variants. Evidence based guidelines are essential for implementing …

Pharmacogenomics in the clinic

MV Relling, WE Evans - Nature, 2015 - nature.com
After decades of discovery, inherited variations have been identified in approximately 20
genes that affect about 80 medications and are actionable in the clinic. And some …

Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between CYP2D6, CYP3A4 and CYP1A2 and antipsychotics

L Beunk, M Nijenhuis, B Soree… - European Journal of …, 2024 - nature.com
Abstract The Dutch Pharmacogenetics Working Group (DPWG) aims to facilitate
pharmacogenetics implementation in clinical practice by developing evidence-based …

Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene–drug interaction of DPYD and fluoropyrimidines

CATC Lunenburg, CH van der Wouden… - European Journal of …, 2020 - nature.com
Despite advances in the field of pharmacogenetics (PGx), clinical acceptance has remained
limited. The Dutch Pharmacogenetics Working Group (DPWG) aims to facilitate PGx …

PharmGKB: a worldwide resource for pharmacogenomic information

JM Barbarino, M Whirl‐Carrillo… - … : Systems Biology and …, 2018 - Wiley Online Library
As precision medicine becomes increasingly relevant in healthcare, the field of
pharmacogenomics (PGx) also continues to gain prominence in the clinical setting. Leading …

Pharmacogenetics: from bench to byte—an update of guidelines

JJ Swen, M Nijenhuis, A de Boer… - Clinical …, 2011 - Wiley Online Library
Currently, there are very few guidelines linking the results of pharmacogenetic tests to
specific therapeutic recommendations. Therefore, the Royal Dutch Association for the …

Implementing pharmacogenomics in Europe: design and implementation strategy of the ubiquitous pharmacogenomics consortium

CH van der Wouden… - Clinical …, 2017 - Wiley Online Library
Despite scientific and clinical advances in the field of pharmacogenomics (PGx), application
into routine care remains limited. Opportunely, several implementation studies and …

Proton pump inhibitors: from CYP2C19 pharmacogenetics to precision medicine

N El Rouby, JJ Lima, JA Johnson - Expert opinion on drug …, 2018 - Taylor & Francis
ABSTRACT Introduction: Proton Pump inhibitors (PPIs) are commonly used for a variety of
acid related disorders. Despite the overall effectiveness and safety profile of PPIs, some …

Preemptive clinical pharmacogenetics implementation: current programs in five US medical centers

HM Dunnenberger, KR Crews… - Annual review of …, 2015 - annualreviews.org
Although the field of pharmacogenetics has existed for decades, practioners have been slow
to implement pharmacogenetic testing in clinical care. Numerous publications describe the …

Comparison of the guidelines of the clinical pharmacogenetics implementation consortium and the dutch pharmacogenetics working group

PCD Bank, KE Caudle, JJ Swen… - Clinical …, 2018 - Wiley Online Library
Both the Clinical Pharmacogenetics Implementation Consortium (CPIC) and Dutch
Pharmacogenetics Working Group provide therapeutic recommendations for well‐known …